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AIMP1 Antikörper (AA 201-300)

This anti-AIMP1 antibody (ABIN759656) is a Rabbit Polyclonal antibody detecting AIMP1 in WB, ELISA, IF (cc), IF (p), IHC (p), IHC (fro). Suitable for Human.
Produktnummer ABIN759656

Kurzübersicht für AIMP1 Antikörper (AA 201-300) (ABIN759656)

Target

Alle AIMP1 Antikörper anzeigen
AIMP1 (Aminoacyl tRNA Synthetase Complex-Interacting Multifunctional Protein 1 (AIMP1))

Reaktivität

  • 66
  • 20
  • 15
  • 4
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
Human

Wirt

  • 55
  • 9
  • 7
Kaninchen

Klonalität

  • 62
  • 9
Polyklonal

Konjugat

  • 41
  • 7
  • 3
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Dieser AIMP1 Antikörper ist unkonjugiert

Applikation

  • 57
  • 24
  • 17
  • 12
  • 12
  • 11
  • 10
  • 7
  • 7
  • 5
  • 5
  • 3
  • 3
  • 2
  • 1
Western Blotting (WB), ELISA, Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))
  • Bindungsspezifität

    • 14
    • 7
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 201-300

    Kreuzreaktivität

    Human

    Homologie

    Mouse,Rat,Dog,Cow,Pig,Rabbit

    Aufreinigung

    Purified by Protein A.

    Immunogen

    KLH conjugated synthetic peptide derived from human EMAP2

    Isotyp

    IgG
  • Applikationshinweise

    WB 1:300-5000
    ELISA 1:500-1000
    IHC-P 1:200-400
    IHC-F 1:100-500
    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200

    Beschränkungen

    Nur für Forschungszwecke einsetzbar
  • Format

    Liquid

    Konzentration

    1 μg/μL

    Buffer

    0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

    Konservierungsmittel

    ProClin

    Vorsichtsmaßnahmen

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

    Lagerung

    4 °C,-20 °C

    Informationen zur Lagerung

    Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

    Haltbarkeit

    12 months
  • Target

    AIMP1 (Aminoacyl tRNA Synthetase Complex-Interacting Multifunctional Protein 1 (AIMP1))

    Andere Bezeichnung

    EMAP2

    Hintergrund

    Synonyms: AIMP 1, Aimp1, AIMP1/p43, AIMP1_HUMAN , Aminoacyl tRNA synthetase complex-interacting multunctional protein 1, ARS interacting multunctional protein 1, ARS-interacting multunctional protein 1, EMAP 2, EMAP-2, EMAP-II, EMAP II, EMAP2, EMAPII, Endothelial monocyte activating polypeptide 2, Endothelial Monocyte Activating Polypeptide, Endothelial monocyte-activating polypeptide 2, Endothelial monocyte-activating polypeptide II, Multisynthase complex auxiliary component p43, Multisynthetase complex auxiliary component p43, p43 antibody Scye 1, Scye1, Small Inducible Cytokine Subfamily E Member 1, Small inducible cytokine subfamily E, member 1 endothelial monocyte-activating.

    Background: Non-catalytic component of the multisynthase complex. Stimulates the catalytic activity of cytoplasmic arginyl-tRNA synthase. Binds tRNA. Possesses inflammatory cytokine activity. Negatively regulates TGF-beta signaling through stabilization of SMURF2 by binding to SMURF2 and inhibiting its SMAD7-mediated degradation. Involved in glucose homeostasis through induction of glucagon secretion at low glucose levels. Promotes dermal fibroblast proliferation and wound repair. Regulates KDELR1-mediated retention of HSP90B1/gp96 in the endoplasmic reticulum. Plays a role in angiogenesis by inducing endothelial cell migration at low concentrations and endothelian cell apoptosis at high concentrations. Induces maturation of dendritic cells and monocyte cell adhesion. Modulates endothelial cell responses by degrading HIF-1A through interaction with PSMA7.

    Gen-ID

    9255
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