RHOA Antikörper (pSer188) (Cy5)

Produktnummer ABIN758246

Der Kaninchen Polyklonal anti-RHOA Antikörper wird verwendet zum Nachweis von RHOA in Proben von Human, Maus und Ratte. Er wurde validiert für WB, FACS, IF (cc) und IF (p).

Kurzübersicht für RHOA Antikörper (pSer188) (Cy5) (ABIN758246)

Target: RHOA (Ras Homolog Gene Family, Member A (RHOA))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser RHOA Antikörper ist konjugiert mit Cy5

Applikation: Western Blotting (WB), Flow Cytometry (FACS), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Produktdetails anti-RHOA Antikörper (Cy5)

Bindungsspezifität: pSer188

Kreuzreaktivität: Human, Maus, Ratte

Homologie: Dog,Cow,Sheep,Chicken

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic phosphopeptide derived from human RhoA around the phosphorylation site of Ser188

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: FCM 1:20-100
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Haltbarkeit: 12 months

Details zu RHOA

Target: RHOA (Ras Homolog Gene Family, Member A (RHOA))

Andere Bezeichnung: RhoA

Hintergrund:

Synonyms: RHOAphospho S188, RhoA protein, Aplysia ras related homolog 12, ARH 12, ARH12, ARHA, H 12, Oncogene RHO H12, Ras homolog gene family member A, RHO 12, Rho A, RHO H12, RHO12, RHOH 12, RHOH12, Small GTP binding protein Rho A, Small GTP binding protein RhoA, Transforming protein Rho A, Transforming protein RhoA.

Background: This gene encodes a member of the Rho family of small GTPases, which cycle between inactive GDP-bound and active GTP-bound states and function as molecular switches in signal transduction cascades. Rho proteins promote reorganization of the actin cytoskeleton and regulate cell shape, attachment, and motility. The protein encoded by this gene is prenylated at its C-terminus, and localizes to the cytoplasm and plasma membrane. It is thought to be important in cell locomotion. Overexpression of this gene is associated with tumor cell proliferation and metastasis. Multiple alternatively spliced variants, encoding the same protein, have been identified.

Gen-ID: 387

Pathways: Microtubule Dynamics, WNT Signalweg, Neurotrophin Signalübertragung, Intracellular Steroid Hormone Receptor Signaling Pathway, Regulation of Intracellular Steroid Hormone Receptor Signaling, Regulation of Actin Filament Polymerization, Cell-Cell Junction Organization, Positive Regulation of Endopeptidase Activity, Signaling Events mediated by VEGFR1 and VEGFR2, Thromboxane A2 Receptor Signaling, SARS-CoV-2 Protein Interaktom