SNRPE Antikörper (pThr401) (Cy3)
Kurzübersicht für SNRPE Antikörper (pThr401) (Cy3) (ABIN756685)
Target
Alle SNRPE Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- pThr401
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Kreuzreaktivität
- Maus
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Homologie
- Human,Rat,Dog,Cow,Pig,Horse,Chicken,Rabbit
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Aufreinigung
- Purified by Protein A.
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Immunogen
- KLH conjugated synthetic phosphopeptide derived from human B-Raf around the phosphorylation site of Thr401
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Isotyp
- IgG
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Applikationshinweise
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IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200 -
Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Konzentration
- 1 μg/μL
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Buffer
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
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Konservierungsmittel
- ProClin
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Vorsichtsmaßnahmen
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
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Haltbarkeit
- 12 months
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- SNRPE (Small Nuclear Ribonucleoprotein Polypeptide E (SNRPE))
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Andere Bezeichnung
- B-Raf
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Hintergrund
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Synonyms: B Raf phospho T401, p-B Raf phospho T401, 94 kDa B raf protein, B raf 1, B Raf proto oncogene serine threonine protein kinase, BRAF 1, Braf, BRAF1, cRmil, MGC126806, MGC138284, Murine sarcoma viral v-raf oncogene homolog B1, Murine sarcoma viral v raf oncogene homolog B1, p94, RAFB 1, RAFB1, v raf murine sarcoma viral oncogene homolog B1, FLJ95109, BRAF_HUMAN.
Background: The Raf kinases are important intermediates in signal transduction. Raf protein family members, including A Raf and B Raf, have intrinsic serine/threonine kinase activity. Interaction between Ras proteins and Raf proteins results in Raf-mediated phosphorylation and activation of MEK (also known as MAP kinase kinase). Defects in BRAF are involved in a wide range of cancers. B-Raf is a serine/threonine protein kinase that acts as a signal transducer from membrane-associated receptors to nuclear transcription factors. 1 BRAF is important for the regulation of cell proliferation and determination of cell fate during embryogenesis. BRAF acts downstream of Ras and upstream of MEK in the Ras-Raf-MEK-ERK signal transduction pathway, which is a conserved RAS-activated protein kinase cascade that regulates cell growth, proliferation, and differentiation in response to growth factors, cytokines, and hormones.
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Gen-ID
- 673
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Pathways
- Ribonucleoprotein Complex Subunit Organization, Hepatitis C
Target
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