SNRPE Antikörper (Internal Region)

Produktnummer ABIN2854894

Produktdetails anti-SNRPE Antikörper

Target: SNRPE (Small Nuclear Ribonucleoprotein Polypeptide E (SNRPE))

Bindungsspezifität: Internal Region

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser SNRPE Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunoprecipitation (IP)

Produktmerkmale: Rabbit polyclonal antibody to B-Raf (v-raf murine sarcoma viral oncogene homolog B1)
B-Raf antibody [N2C1], Internal

Aufreinigung: Purified by antigen-affinity chromatography.

Immunogen: Recombinant protein encompassing a sequence within the center region of human B-Raf. The exact sequence is proprietary.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Suggested dilution Reference IHC (Formalin-fixed paraffin-embedded sections) 1:100-1:1000* Immunoprecipitation 1:100-1:500* Western blot 1:500-1:10000* Not tested in other applications. *Optimal dilutions/concentrations should be determined by the researcher.Suggested dilutionReferenceIHC (Formalin-fixed paraffin-embedded sections)1:100-1:1000* Immunoprecipitation1:100-1:500* Western blot1:500-1:10000*

Kommentare:

Positive Control: A549 , H1299 , HCT116 , PC-12

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: 1XPBS, 1 % BSA, 20 % Glycerol ( pH 7). 0.01 % Thimerosal was added as a preservative.

Konservierungsmittel: Thimerosal (Merthiolate)

Vorsichtsmaßnahmen: This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Keep as concentrated solution. Aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.

Details zu SNRPE

Target: SNRPE (Small Nuclear Ribonucleoprotein Polypeptide E (SNRPE))

Andere Bezeichnung: B-Raf (SNRPE Produkte)

Synonyme: B-raf antikoerper, HYPT11 antikoerper, SME antikoerper, Sm-E antikoerper, b-raf antikoerper, sm-e antikoerper, sme antikoerper, SmE antikoerper, snRNP-E antikoerper, AL022645 antikoerper, C76690 antikoerper, zgc:56682 antikoerper, small nuclear ribonucleoprotein polypeptide E antikoerper, small nuclear ribonucleoprotein polypeptide E L homeolog antikoerper, small nuclear ribonucleoprotein E antikoerper, SNRPE antikoerper, snrpe.L antikoerper, Snrpe antikoerper, snrpe antikoerper

Hintergrund: This gene encodes a protein belonging to the raf/mil family of serine/threonine protein kinases. This protein plays a role in regulating the MAP kinase/ERKs signaling pathway, which affects cell division, differentiation, and secretion. Mutations in this gene are associated with cardiofaciocutaneous syndrome, a disease characterized by heart defects, mental retardation and a distinctive facial appearance. Mutations in this gene have also been associated with various cancers, including non-Hodgkin lymphoma, colorectal cancer, malignant melanoma, thyroid carcinoma, non-small cell lung carcinoma, and adenocarcinoma of lung. A pseudogene, which is located on chromosome X, has been identified for this gene.

Cellular Localization: Cytoplasm

Molekulargewicht: 84 kDa

Gen-ID: 673

Pathways: Ribonucleoprotein Complex Subunit Organization, Hepatitis C