Vitronectin Antikörper

Produktnummer ABIN8065534

Der Maus Monoklonal anti-Vitronectin Antikörper (Klon HV23) (ABIN8065534) detektiert spezifisch Vitronectin in WB und ELISA. Dieser Antikörper reagiert spezifisch mit Proben aus Human.

Kurzübersicht für Vitronectin Antikörper (ABIN8065534)

Target: Vitronectin (VTN)

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser Vitronectin Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA

Güteklasse: Carrier-free

Klon: HV23

Produktdetails anti-Vitronectin Antikörper

Verwendungszweck: Anti-Vitronectin Antibody

Spezifität: CSI 003-23 is highly specific for vitronectin. There is no evidence for cross-reactivity with other connective tissue proteins (fibronectin, elastin, collagen, laminin). CSI 003-23 binds nearly as well to native vitronectin as to denatured. CSI 003-23 is a potent inhibitor of integrin-mediated cell adhesion to vitronectin and a moderate inhibitor of PAI-1 binding. Epitope is located in the somatomedin B domain

Homologie: Canine,Feline,Goat,Horse,and Human

Aufreinigung: Protein A or Protein G purified

Immunogen: Human vitronectin purified from plasma by heparin-affinity chromatography

Isotyp: IgG1, kappa

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: 0.01 M phosphate buffer, pH 7.4, with 0.5 M NaCl and 15 mM sodium azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C

Informationen zur Lagerung: 2-8°C without exposure to light

Haltbarkeit: 24 months

Details zu Vitronectin

Target: Vitronectin (VTN)

Andere Bezeichnung: Vitronectin

Hintergrund: VTN, V75, VN, VNT, vitronectin, complement S-protein, epibolin, serum spreading factor, somatomedin B,Vitronectin is a cell adhesion and spreading factor found in serum and tissues. Vitronectin interact with glycosaminoglycans and proteoglycans. Is recognized by certain members of the integrin family and serves as a cell-to-substrate adhesion molecule. Inhibitor of the membrane-damaging effect of the terminal cytolytic complement pathway., Somatomedin-B is a growth hormone-dependent serum factor with protease-inhibiting activity.,VTN,Vitronectin is a plasma glycoprotein that circulates in the blood. Vitronectin is circulating as a mixture of both 75 kDa and 65 kDa forms. Vitronectin is a major cell adhesive glycoprotein and is a common component of extracellular matrix and plasma. It competes effectively with other plasma proteins and is often involved in cell attachment, regulation of blood coagulation and immune responses. It has similar tissue distribution to fibronectin and also its integrin receptor recognizes fibronectin. (2)

Molekulargewicht: 65 kDa, 75 kDA

Gen-ID: 7448

UniProt: P04004

Pathways: Autophagie, Smooth Muscle Cell Migration