WWOX Antikörper (AA 1-245) (Cy3)

Produktnummer ABIN8054547

Der Maus Monoklonal anti-WWOX Antikörper wird verwendet zum Nachweis von WWOX in Proben von Human, Maus und Ratte. Er wurde validiert für FACS.

Kurzübersicht für WWOX Antikörper (AA 1-245) (Cy3) (ABIN8054547)

Target: WWOX (WW Domain Containing Oxidoreductase (WWOX))

Reaktivität: Human, Maus, Ratte

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser WWOX Antikörper ist konjugiert mit Cy3

Applikation: Flow Cytometry (FACS)

Klon: 3D10

Produktdetails anti-WWOX Antikörper (Cy3)

Bindungsspezifität: AA 1-245

Verwendungszweck: Anti-WWOX Antibody (monoclonal, 3D10) Cy3 Conjugated

Spezifität: No cross reactivity with other proteins.

Kreuzreaktivität (Details): No cross-reactivity with other proteins.

Aufreinigung: Immunogen affinity purified.

Immunogen: E. coli-derived human WWOX recombinant protein (Position: M1-D245).

Isotyp: IgG1

Anwendungsinformationen

Applikationshinweise: Flow Cytometry, 1-3 μg/1x10⁶ cells

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Haltbarkeit: 12 months

Details zu WWOX

Target: WWOX (WW Domain Containing Oxidoreductase (WWOX))

Andere Bezeichnung: WWOX

Hintergrund:

Background: WW domain-containing oxidoreductase is an enzyme that in humans is encoded by the WWOX gene. This gene encodes a member of the short-chain dehydrogenases/reductases (SDR) protein family. It spans the FRA16D common chromosomal fragile site and appears to function as a tumor suppressor gene. Expression of the encoded protein is able to induce apoptosis, while defects in this gene are associated with multiple types of cancer. Disruption of this gene is also associated with autosomal recessive spinocerebellar ataxia 12. Disruption of a similar gene in mouse results in impaired steroidogenesis, additionally suggesting a metabolic function for the protein. Alternative splicing results in multiple transcript variants.

Gene Full Name: WW domain containing oxidoreductase

Gen-ID: 51741

UniProt: Q9NZC7