STING/TMEM173 Antikörper (C-Term)

Produktnummer ABIN8049063

Der Kaninchen Polyklonal anti-STING/TMEM173 Antikörper wird verwendet zum Nachweis von STING/TMEM173 in Proben von Human und Maus. Er wurde validiert für WB, IHC und FACS.

Kurzübersicht für STING/TMEM173 Antikörper (C-Term) (ABIN8049063)

Target: STING/TMEM173 (TMEM173) (Transmembrane Protein 173 (TMEM173))

Reaktivität: Human, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser STING/TMEM173 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC), Flow Cytometry (FACS)

Güteklasse: Carrier-free

Produktdetails anti-STING/TMEM173 Antikörper

Bindungsspezifität: C-Term

Verwendungszweck: Anti-TMEM173 Antibody

Spezifität: No cross reactivity with other proteins.

Kreuzreaktivität (Details): No cross-reactivity with other proteins

Homologie: different from the related mouse sequence by five amino acids.

Produktmerkmale: Anti-TMEM173 Antibody. Tested in Flow Cytometry, IHC, WB applications. This antibody reacts with Human, Mouse.

Aufreinigung: Immunogen affinity purified.

Immunogen: A synthetic peptide corresponding to a sequence at the C-terminus of human TMEM173, different from the related mouse sequence by five amino acids.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Western blot, 0.1-0.5 μg/mL, Human, Mouse Immunohistochemistry (Paraffin-embedded Section), 2-5 μg/mL, Human Flow Cytometry(Fixed), 1-3 μg/1x10⁶ cells, Human

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Konzentration: 500 μg/mL

Buffer: Each vial contains 4 mg Trehalose, 0.9 mg NaCl and 0.2 mg Na2HPO4.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.

Haltbarkeit: 12 months

Details zu STING/TMEM173

Target: STING/TMEM173 (TMEM173) (Transmembrane Protein 173 (TMEM173))

Andere Bezeichnung: TMEM173

Hintergrund:

Background: Transmembrane protein 173 is a protein that in humans is encoded by the TMEM173 gene. This gene encodes a five transmembrane protein that functions as a major regulator of the innate immune response to viral and bacterial infections. The encoded protein is a pattern recognition receptor that detects cytosolic nucleic acids and transmits signals that activate type I interferon responses. Also the encoded protein has been shown to play a role in apoptotic signaling by associating with type II major histocompatibility complex. Mutations in this gene are the cause of infantile-onset STING-associated vasculopathy. Alternate splicing results in multiple transcript variants.

Gene Full Name: stimulator of interferon response cGAMP interactor 1

Sequence Similarities: Belongs to the transcription factor STAT family.

Molekulargewicht: 35 kDa

Gen-ID: 340061

UniProt: Q86WV6

Pathways: Activation of Innate immune Response