TRAF3IP2 Antikörper (AA 1-528) (Fluoro488)

Produktnummer ABIN8047701

Der Kaninchen Polyklonal anti-TRAF3IP2 Antikörper wird verwendet zum Nachweis von TRAF3IP2 in Proben von Human, Ratte und Maus. Er wurde validiert für FACS.

Kurzübersicht für TRAF3IP2 Antikörper (AA 1-528) (Fluoro488) (ABIN8047701)

Target: TRAF3IP2 (TRAF3 Interacting Protein 2 (TRAF3IP2))

Reaktivität: Human, Ratte, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser TRAF3IP2 Antikörper ist konjugiert mit Fluoro488

Applikation: Flow Cytometry (FACS)

Produktdetails anti-TRAF3IP2 Antikörper (Fluoro488)

Bindungsspezifität: AA 1-528

Verwendungszweck: Anti-TRAF3IP2 Antibody Fluoro488 Conjugated

Kreuzreaktivität (Details): No cross-reactivity with other proteins

Homologie: Human TRAF3IP2 shares 77% amino acid (aa) sequence identity with mouse TRAF3IP2.

Aufreinigung: Immunogen affinity purified.

Immunogen: E.coli-derived human TRAF3IP2 recombinant protein (Position: M1-H528). Human TRAF3IP2 shares 77% amino acid (aa) sequence identity with mouse TRAF3IP2.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Flow Cytometry, Optimal dilutions should be determined by end users.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Haltbarkeit: 12 months

Details zu TRAF3IP2

Target: TRAF3IP2 (TRAF3 Interacting Protein 2 (TRAF3IP2))

Andere Bezeichnung: TRAF3IP2

Hintergrund:

Background: This gene encodes a protein involved in regulating responses to cytokines by members of the Rel/NF-kappaB transcription factor family. These factors play a central role in innate immunity in response to pathogens, inflammatory signals and stress. This gene product interacts with TRAF proteins (tumor necrosis factor receptor-associated factors) and either I-kappaB kinase or MAP kinase to activate either NF-kappaB or Jun kinase. Several alternative transcripts encoding different isoforms have been identified. Another transcript, which does not encode a protein and is transcribed in the opposite orientation, has been identified. Overexpression of this transcript has been shown to reduce expression of at least one of the protein encoding transcripts, suggesting it has a regulatory role in the expression of this gene.

Gene Full Name: TRAF3 interacting protein 2

Gen-ID: 10758

UniProt: O43734

Pathways: Production of Molecular Mediator of Immune Response