TRAF3IP2 Antikörper (C-Term)

Produktnummer ABIN1537357

Dieser Kaninchen Polyklonal Antikörper detektiert spezifisch TRAF3IP2 in WB. Es zeigt Reaktivität gegenüber Proben von Human.

Kurzübersicht für TRAF3IP2 Antikörper (C-Term) (ABIN1537357)

Target: TRAF3IP2 (TRAF3 Interacting Protein 2 (TRAF3IP2))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser TRAF3IP2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Klon: RB39771

Produktdetails anti-TRAF3IP2 Antikörper

Bindungsspezifität: AA 463-492, C-Term

Aufreinigung: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This TRAF3IP2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 463-492 amino acids from the C-terminal region of human TRAF3IP2.

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: WB: 1:1000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: TRAF3IP2 Antibody (C-term) can be refrigerated at 2-8 °C for up to 6 months. For long term storage, keep at -20 °C.

Haltbarkeit: 6 months

Details zu TRAF3IP2

Target: TRAF3IP2 (TRAF3 Interacting Protein 2 (TRAF3IP2))

Andere Bezeichnung: TRAF3IP2

Hintergrund: This gene encodes a protein involved in regulating responses to cytokines by members of the Rel/NF-kappaB transcription factor family. These factors play a central role in innate immunity in response to pathogens, inflammatory signals and stress. This gene product interacts with TRAF proteins (tumor necrosis factor receptor-associated factors) and either I-kappaB kinase or MAP kinase to activate either NF-kappaB or Jun kinase. Several alternative transcripts encoding different isoforms have been identified. Another transcript, which does not encode a protein and is transcribed in the opposite orientation, has been identified. Overexpression of this transcript has been shown to reduce expression of at least one of the protein encoding transcripts, suggesting it has a regulatory role in the expression of this gene.

Molekulargewicht: 64666

Gen-ID: 10758

NCBI Accession: NP_001157753, NP_001157755, NP_679211

UniProt: O43734

Pathways: Production of Molecular Mediator of Immune Response