Thymic Stromal Lymphopoietin Antikörper (C-Term) (HRP)

Produktnummer ABIN8046473

Dieser Kaninchen Polyklonal Antikörper detektiert spezifisch Thymic Stromal Lymphopoietin in WB, IHC und ELISA. Es zeigt Reaktivität gegenüber Proben von Human und Maus.

Kurzübersicht für Thymic Stromal Lymphopoietin Antikörper (C-Term) (HRP) (ABIN8046473)

Target: Thymic Stromal Lymphopoietin (TSLP)

Reaktivität: Human, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Thymic Stromal Lymphopoietin Antikörper ist konjugiert mit HRP

Applikation: Western Blotting (WB), Immunohistochemistry (IHC), ELISA

Produktdetails anti-Thymic Stromal Lymphopoietin Antikörper (HRP)

Bindungsspezifität: C-Term

Verwendungszweck: Anti-TSLP Antibody HRP Conjugated

Spezifität: No cross reactivity with other proteins.

Kreuzreaktivität (Details): No cross-reactivity with other proteins.

Aufreinigung: Immunogen affinity purified.

Immunogen: A synthetic peptide corresponding to a sequence at the C-terminus of human TSLP.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Western blot, Optimal dilutions should be determined by end users. Immunohistochemistry (Paraffin-embedded Section), Optimal dilutions should be determined by end users. ELISA, Optimal dilutions should be determined by end users.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4.

Lagerung: -20 °C

Informationen zur Lagerung: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing.

Haltbarkeit: 12 months

Details zu Thymic Stromal Lymphopoietin

Target: Thymic Stromal Lymphopoietin (TSLP)

Andere Bezeichnung: TSLP

Hintergrund:

Background: Thymic stromal lymphopoietin, also called TSLP is a protein belonging to the cytokine family. This gene is mapped to 5q22.1. It encodes a hemopoietic cytokine proposed to signal through a heterodimeric receptor complex composed of the thymic stromal lymphopoietin receptor and the IL-7R alpha chain. It mainly impacts myeloid cells and induces the release of T cell-attracting chemokines from monocytes and enhances the maturation of CD11c (+) dendritic cells. The protein promotes T helper type 2 (TH2) cell responses that are associated with immunity in various inflammatory diseases, including asthma, allergic inflammation and chronic obstructive pulmonary disease. The protein is therefore considered a potential therapeutic target for the treatment of such diseases.

Gene Full Name: thymic stromal lymphopoietin

Gen-ID: 85480

UniProt: Q969D9