Thrombopoietin Antikörper (AA 22-258)

Produktnummer ABIN8046345

Der Kaninchen Polyklonal anti-Thrombopoietin Antikörper wird verwendet zum Nachweis von Thrombopoietin in Proben von Human. Er wurde validiert für WB und ELISA.

Kurzübersicht für Thrombopoietin Antikörper (AA 22-258) (ABIN8046345)

Target: Thrombopoietin (THPO)

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Thrombopoietin Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA

Güteklasse: Carrier-free

Produktdetails anti-Thrombopoietin Antikörper

Bindungsspezifität: AA 22-258

Verwendungszweck: Anti-Thrombopoietin/THPO Antibody

Spezifität: No cross reactivity with other proteins.

Kreuzreaktivität (Details): No cross-reactivity with other proteins.

Homologie: coli-derived human Thrombopoietin,TPO recombinant protein (Position: S22-R258). Human Thrombopoietin,TPO shares 79.3%,80.6% amino acid (aa) sequence identity with mouse,rat Thrombopoietin,TPO,respectively.

Produktmerkmale: Anti-Thrombopoietin/THPO Antibody. Tested in ELISA, WB applications. This antibody reacts with Human.

Aufreinigung: Immunogen affinity purified.

Immunogen: E. coli-derived human Thrombopoietin/TPO recombinant protein (Position: S22-R258). Human Thrombopoietin/TPO shares 79.3% and 80.6% amino acid (aa) sequence identity with mouse and rat Thrombopoietin/TPO, respectively.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: ELISA, 0.1-0.5 μg/mL, -Western blot, 0.1-0.5 μg/mL, Human

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Konzentration: 500 μg/mL

Buffer: Each vial contains antibody formulated with stabilizing components, 0.9 mg NaCl, 0.2 mg Na2HPO4, and 0.05 mg Sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.

Haltbarkeit: 12 months

Details zu Thrombopoietin

Target: Thrombopoietin (THPO)

Andere Bezeichnung: THPO

Hintergrund:

Background: Thrombopoietin (THPO), also known as megakaryocyte growth and development factor (MGDF), is a protein that in humans is encoded by the THPO gene. Megakaryocytopoiesis is the cellular development process that leads to platelet production. The main functional protein encoded by this gene is a humoral growth factor that is necessary for megakaryocyte proliferation and maturation, as well as for thrombopoiesis. This protein is the ligand for MLP/C_MPL, the product of myeloproliferative leukemia virus oncogene. Mutations in this gene are the cause of thrombocythemia 1. Alternative promoter usage and differential splicing result in multiple transcript variants differing in the 5' UTR and/or coding region. Multiple AUG codons upstream of the main open reading frame (ORF) have been identified, and these upstream AUGs inhibit translation of the main ORF at different extent.

Gene Full Name: thrombopoietin

Molekulargewicht: 45 kDa

Gen-ID: 7066

UniProt: P40225

Pathways: JAK-STAT Signalweg, Hormone Activity