TXNRD2 Antikörper (C-Term)

Produktnummer ABIN8046268

Der Kaninchen Polyklonal anti-TXNRD2 Antikörper (ABIN8046268) detektiert spezifisch TXNRD2 in WB und IHC. Dieser Antikörper reagiert spezifisch mit Proben aus Human und Ratte.

Kurzübersicht für TXNRD2 Antikörper (C-Term) (ABIN8046268)

Target: TXNRD2 (Thioredoxin Reductase 2 (TXNRD2))

Reaktivität: Human, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser TXNRD2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC)

Güteklasse: Carrier-free

Produktdetails anti-TXNRD2 Antikörper

Bindungsspezifität: C-Term

Verwendungszweck: Anti-TXNRD2 Antibody

Spezifität: No cross reactivity with other proteins.

Kreuzreaktivität (Details): No cross-reactivity with other proteins

Homologie: different from the related rat sequence by three amino acids,and from the related mouse sequence by two amino acids.

Produktmerkmale: Anti-TXNRD2 Antibody. Tested in IHC, WB applications. This antibody reacts with Human, Rat.

Aufreinigung: Immunogen affinity purified.

Immunogen: A synthetic peptide corresponding to a sequence at the C-terminus of human TXNRD2, different from the related rat sequence by three amino acids, and from the related mouse sequence by two amino acids.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Immunohistochemistry (Paraffin-embedded Section), 0.5-1 μg/mL, Human, RatWestern blot, 0.1-0.5 μg/mL, Human, Rat

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Konzentration: 500 μg/mL

Buffer: Each vial contains antibody formulated with stabilizing components, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Thimerosal, 0.05 mg Sodium azide.

Konservierungsmittel: Sodium azide, Thimerosal (Merthiolate)

Vorsichtsmaßnahmen: This product contains Thimerosal (Merthiolate) and Sodium azide: POISONOUS AND HAZARDOUS SUBSTANCES which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.

Haltbarkeit: 12 months

Details zu TXNRD2

Target: TXNRD2 (Thioredoxin Reductase 2 (TXNRD2))

Andere Bezeichnung: TXNRD2

Hintergrund:

Background: TXNRD2 (Thioredoxin reductase 2), also known as TRXR2, TR3, SELZ, or TR-BETA, Thioredoxin reductases, are selenocysteine (sec)-containing flavoenzymes that maintain thioredoxins, small proteins that catalyze redox reactions, in the reduced state using the reducing power of NADPH. By STS analysis and genomic sequence analysis, respectively, Miranda-Vizuete et al. (1999) and Sun et al. (1999) mapped the TXNRD2 gene to chromosome 22q11.2. Miranda-Vizuete et al. (1999) mapped the mouse gene to chromosome 16. Gasdaska et al. (1999) showed that TXNRD2 was a thioredoxin reductase that could ly reduce proteins such as insulin.

Gene Full Name: thioredoxin reductase 2

Sequence Similarities: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.

Molekulargewicht: 110 kDa

Gen-ID: 10587

UniProt: Q9NNW7

Pathways: Cell RedoxHomeostasis