TXNRD2 Antikörper (AA 440-520)

Produktnummer ABIN7217394

Der Kaninchen Polyklonal anti-TXNRD2 Antikörper wird verwendet zum Nachweis von TXNRD2 in Proben von Human, Maus und Ratte. Er wurde validiert für WB, IHC, ELISA und IF.

Kurzübersicht für TXNRD2 Antikörper (AA 440-520) (ABIN7217394)

Target: TXNRD2 (Thioredoxin Reductase 2 (TXNRD2))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser TXNRD2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Immunofluorescence (IF)

Produktdetails anti-TXNRD2 Antikörper

Bindungsspezifität: AA 440-520

Verwendungszweck: Rabbit Anti-TrxR2 Polyclonal Antibody

Spezifität: TrxR2 Polyclonal Antibody detects endogenous levels of TrxR2 protein.

Aufreinigung: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from the C-terminal region of human TrxR2 at AA range: 440-520

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-1:2000,IHC 1:100-1:300,ELISA 1:10000,IF 1:50-200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Haltbarkeit: 12 months

Details zu TXNRD2

Target: TXNRD2 (Thioredoxin Reductase 2 (TXNRD2))

Andere Bezeichnung: TrxR2

Hintergrund: TXNRD2, KIAA1652, TRXR2, Thioredoxin reductase 2, mitochondrial, Selenoprotein Z, SelZ, TR-beta, Thioredoxin reductase TR3TXNRD2 encodes a member of the class I pyridine nucleotide-disulfide oxidoreductase family. The thioredoxin reductase 2 mitochondrial is a selenocysteine-containing flavoenzyme that maintains thioredoxins in a reduced state, thereby playing a key role in regulating the cellular redox environment. Mammals have three related thioredoxin reductases. This gene encodes a mitochondrial form important for scavenging of reactive oxygen species in mitochondria. Alternatively spliced transcript variants encoding different isoforms have been described.

Molekulargewicht: 56kD

Gen-ID: 10587

UniProt: Q9NNW7

Pathways: Cell RedoxHomeostasis