TBP Antikörper (AA 38-107) (Biotin)

Produktnummer ABIN8045486

Dieser Kaninchen Polyklonal Antikörper detektiert spezifisch TBP in WB, IHC und ELISA. Es zeigt Reaktivität gegenüber Proben von Maus und Ratte.

Kurzübersicht für TBP Antikörper (AA 38-107) (Biotin) (ABIN8045486)

Target: TBP (TATA Box Binding Protein (TBP))

Reaktivität: Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser TBP Antikörper ist konjugiert mit Biotin

Applikation: Western Blotting (WB), Immunohistochemistry (IHC), ELISA

Produktdetails anti-TBP Antikörper (Biotin)

Bindungsspezifität: AA 38-107

Verwendungszweck: Anti-TATA binding protein TBP Antibody Biotin Conjugated

Spezifität: No cross reactivity with other proteins.

Kreuzreaktivität (Details): No cross-reactivity with other proteins.

Aufreinigung: Immunogen affinity purified.

Immunogen: E. coli-derived mouse Tbp recombinant protein (Position: L38-A107).

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Western blot, Optimal dilutions should be determined by end users. Immunohistochemistry (Paraffin-embedded Section), Optimal dilutions should be determined by end users. ELISA, Optimal dilutions should be determined by end users.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing.

Haltbarkeit: 12 months

Details zu TBP

Target: TBP (TATA Box Binding Protein (TBP))

Andere Bezeichnung: Tbp

Hintergrund:

Background: TBP, TATA-binding protein, is a general transcription factor that binds specifically to a DNA sequence called the TATA box. The TBP gene is mapped to 6q27. This DNA sequence is found about 35 base pairs upstream of the transcription start site in some eukaryotic gene promoters. TBP, along with a variety of TBP-associated factors, make up the TFIID, a general transcription factor that in turn makes up part of the RNA polymerase II preinitiation complex. As one of the few proteins in the preinitiation complex that binds DNA in a sequence-specific manner, it helps position RNA polymerase II over the transcription start site of the gene. However, it is estimated that only 10-20 % of human promoters have TATA boxes. Therefore, TBP is probably not the only protein involved in positioning RNA polymerase II.

Gene Full Name: TATA box binding protein

Gen-ID: 21374

UniProt: P29037

Pathways: WNT Signalweg