TNIK Antikörper (AA 1281-1360)

Produktnummer ABIN754828

Dieses Kaninchen Polyklonal-Antikörper erkennt spezifisch TNIK in ELISA, IHC (p), IF (p), IF (cc) und IHC (fro). Er zeigt eine Reaktivität gegenüber Maus und Ratte.

Kurzübersicht für TNIK Antikörper (AA 1281-1360) (ABIN754828)

Target: TNIK (TRAF2 and NCK Interacting Kinase (TNIK))

Reaktivität: Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser TNIK Antikörper ist unkonjugiert

Applikation: ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunofluorescence (Cultured Cells) (IF (cc)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Produktdetails anti-TNIK Antikörper

Bindungsspezifität: AA 1281-1360

Kreuzreaktivität: Maus, Ratte

Homologie: Human,Cow,Pig,Horse,Chicken,Rabbit

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human TNIK

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Haltbarkeit: 12 months

Details zu TNIK

Target: TNIK (TRAF2 and NCK Interacting Kinase (TNIK))

Andere Bezeichnung: TNIK

Hintergrund:

Synonyms: Traf2 and NCK interacting kinase, 1500031A17RIK, 4831440I19RIK, AI451411, C530008O15Rik, C630040K21RIK, KIAA0551, MGC189819, MGC189859, RGD1561817, TNIK, TNIK_HUMAN, TRAF2 and NCK-interacting protein kinase.

Background: TNIK is a MSN protein kinase that interacts with both TNF receptor-associated factor 2 (TRAF2) and the adapter protein NCK. The protein has been shown to activate the c-Jun N-terminal kinase pathway when over expressed in Phoenix-A cells. TNIK has been shown to phosphorylate gelsolin, the principal intracellular and extracellular actin-severing protein, in vitro. This and evidence from mutational studies suggest that TNIK functions in the regulation of the cytoskeleton. Northern analysis indicates TNIK expression in human heart, skeletal muscle, and brain, with lower levels of expression in kidney, liver, lung, and pancreas. ESTs have been isolated from human tissue libraries, including normal amnion, gallbladder and skin.

Gen-ID: 23043