SCP2 Antikörper (AA 33-547) (Cy3)

Produktnummer ABIN8042819

Dieser Kaninchen Polyklonal Antikörper detektiert spezifisch SCP2 in FACS. Es zeigt Reaktivität gegenüber Proben von Human, Maus und Ratte.

Kurzübersicht für SCP2 Antikörper (AA 33-547) (Cy3) (ABIN8042819)

Target: SCP2 (Sterol Carrier Protein 2 (SCP2))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser SCP2 Antikörper ist konjugiert mit Cy3

Applikation: Flow Cytometry (FACS)

Produktdetails anti-SCP2 Antikörper (Cy3)

Bindungsspezifität: AA 33-547

Verwendungszweck: Anti-SCP2 Antibody Cy3 Conjugated

Kreuzreaktivität (Details): No cross-reactivity with other proteins

Homologie: Human SCP2 shares 90.5%,88% amino acid (aa) sequence identity with mouse,rat SCP2,respectively.

Aufreinigung: Immunogen affinity purified.

Immunogen: E.coli-derived human SCP2 recombinant protein (Position: R33-L547). Human SCP2 shares 90.5% and 88% amino acid (aa) sequence identity with mouse and rat SCP2, respectively.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Flow Cytometry, Optimal dilutions should be determined by end users.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Haltbarkeit: 12 months

Details zu SCP2

Target: SCP2 (Sterol Carrier Protein 2 (SCP2))

Andere Bezeichnung: SCP2

Hintergrund:

Background: This gene encodes two proteins: sterol carrier protein X (SCPx) and sterol carrier protein 2 (SCP2), as a result of transcription initiation from 2 independently regulated promoters. The transcript initiated from the proximal promoter encodes the longer SCPx protein, and the transcript initiated from the distal promoter encodes the shorter SCP2 protein, with the 2 proteins sharing a common C-terminus. Evidence suggests that the SCPx protein is a peroxisome-associated thiolase that is involved in the oxidation of branched chain fatty acids, while the SCP2 protein is thought to be an intracellular lipid transfer protein. This gene is highly expressed in organs involved in lipid metabolism, and may play a role in Zellweger syndrome, in which cells are deficient in peroxisomes and have impaired bile acid synthesis. Alternative splicing of this gene produces multiple transcript variants, some encoding different isoforms.

Gene Full Name: sterol carrier protein 2

Gen-ID: 6342

UniProt: P22307

Pathways: C21-Steroid Hormone Metabolic Process, Monocarboxylic Acid Catabolic Process