SREBF chaperone Antikörper (AA 1224-1279) (HRP)

Produktnummer ABIN8042168

Dieser Kaninchen Polyklonal Antikörper detektiert spezifisch SREBF chaperone in WB, ELISA und IHC. Es zeigt Reaktivität gegenüber Proben von Human, Maus und Ratte.

Kurzübersicht für SREBF chaperone Antikörper (AA 1224-1279) (HRP) (ABIN8042168)

Target: SREBF chaperone (SCAP)

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser SREBF chaperone Antikörper ist konjugiert mit HRP

Applikation: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Produktdetails anti-SREBF chaperone Antikörper (HRP)

Bindungsspezifität: AA 1224-1279

Verwendungszweck: Anti-SCAP Antibody HRP Conjugated

Kreuzreaktivität (Details): No cross-reactivity with other proteins

Homologie: Human SCAP shares 100% amino acid (aa) sequence identity with both mouse,rat SCAP.

Aufreinigung: Immunogen affinity purified.

Immunogen: E.coli-derived human SCAP recombinant protein (Position: F1224-D1279). Human SCAP shares 100% amino acid (aa) sequence identity with both mouse and rat SCAP.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Western blot, Optimal dilutions should be determined by end users. Immunohistochemistry (Paraffin-embedded Section), Optimal dilutions should be determined by end users. ELISA, Optimal dilutions should be determined by end users.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4.

Lagerung: -20 °C

Informationen zur Lagerung: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing.

Haltbarkeit: 12 months

Details zu SREBF chaperone

Target: SREBF chaperone (SCAP)

Andere Bezeichnung: SCAP

Hintergrund:

Background: This gene encodes a protein with a sterol sensing domain (SSD) and seven WD domains. In the presence of cholesterol, this protein binds to sterol regulatory element binding proteins (SREBPs) and mediates their transport from the ER to the Golgi. The SREBPs are then proteolytically cleaved and regulate sterol biosynthesis. Alternative splicing results in multiple transcript variants.

Gene Full Name: SREBF chaperone

Gen-ID: 22937

UniProt: Q12770

Pathways: SARS-CoV-2 Protein Interaktom