SREBF chaperone Antikörper (AA 604-632)

Produktnummer ABIN652508

Produktdetails anti-SREBF chaperone Antikörper

Target: SREBF chaperone (SCAP)

Bindungsspezifität: AA 604-632

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser SREBF chaperone Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Flow Cytometry (FACS), Immunofluorescence (IF)

Homologie: B, Pig

Aufreinigung: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This SCAP antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 604-632 amino acids from the Central region of human SCAP.

Klon: RB22508

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: IF: 1:100. WB: 1:2000. WB: 1:2000. WB: 1:1000. IHC-P: 1:50~100. FC: 1:25. FC: 1:25

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Haltbarkeit: 6 months

Referenzen für anti-SREBF chaperone Antikörper (ABIN652508)

Takashima, Saitoh, Funabashi, Hirose, Yagi, Nozaki, Sato, Shin, Nakayama: "COPI-mediated retrieval of SCAP is crucial for regulating lipogenesis under basal and sterol-deficient conditions." in: Journal of cell science, Vol. 128, Issue 15, pp. 2805-15, (2015) (PubMed).

Details zu SREBF chaperone

Target: SREBF chaperone (SCAP)

Andere Bezeichnung: SCAP (SCAP Produkte)

Synonyme: 9530044G19 antikoerper, mKIAA0199 antikoerper, SREBF chaperone antikoerper, SREBF chaperone S homeolog antikoerper, SCAP antikoerper, Scap antikoerper, scap.S antikoerper

Hintergrund: SCAP is a protein with a sterol sensing domain(SSD) and seven WD domains. In the presence of cholesterol, this protein binds to sterol regulatory element binding proteins (SREBPs) and mediates their transport from the ER to the Golgi. The SREBPs are then proteolytically cleaved and regulate sterol biosynthesis.

Molekulargewicht: 139729

Gen-ID: 22937

NCBI Accession: NP_036367

UniProt: Q12770

Pathways: SARS-CoV-2 Protein Interaktom