SPOP-B Antikörper (N-Term)

Produktnummer ABIN8041352

Dieser Kaninchen Polyklonal Antikörper detektiert spezifisch SPOP-B in WB. Es zeigt Reaktivität gegenüber Proben von Human.

Kurzübersicht für SPOP-B Antikörper (N-Term) (ABIN8041352)

Target: SPOP-B (Speckle-Type POZ Protein (SPOP-B))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser SPOP-B Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Güteklasse: Carrier-free

Produktdetails anti-SPOP-B Antikörper

Bindungsspezifität: N-Term

Verwendungszweck: Anti-SPOP Antibody

Kreuzreaktivität (Details): No cross-reactivity with other proteins.

Homologie: identical to the related mouse sequences.

Produktmerkmale: Anti-SPOP Antibody. Tested in WB applications. This antibody reacts with Human.

Aufreinigung: Immunogen affinity purified.

Immunogen: A synthetic peptide corresponding to a sequence at the N-terminus of human SPOP, identical to the related mouse sequences.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Western blot, 0.25-0.5 μg/mL, Human

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Konzentration: 500 μg/mL

Buffer: Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.

Haltbarkeit: 12 months

Details zu SPOP-B

Target: SPOP-B (Speckle-Type POZ Protein (SPOP-B))

Andere Bezeichnung: SPOP

Hintergrund:

Background: Speckle-type POZ protein is a protein that in humans is encoded by the SPOP gene. This gene encodes a protein that may modulate the transcriptional repression activities of death-associated protein 6 (DAXX), which interacts with histone deacetylase, core histones, and other histone-associated proteins. In mouse, the encoded protein binds to the putative leucine zipper domain of macroH2A1.2, a variant H2A histone that is enriched on inactivated X chromosomes. The BTB/POZ domain of this protein has been shown in other proteins to mediate transcriptional repression and to interact with components of histone deacetylase co-repressor complexes. Alternative splicing of this gene results in multiple transcript variants encoding the same protein.

Gene Full Name: speckle type BTB/POZ protein

Molekulargewicht: 50 kDa

Gen-ID: 8405

UniProt: O43791