Spartin (SPART) (AA 205-631) Antikörper (Biotin)

Produktnummer ABIN8041320

Der Kaninchen Polyklonal anti-Spartin Antikörper wird verwendet zum Nachweis von Spartin in Proben von Human und Ratte. Er wurde validiert für ELISA, WB und IHC.

Kurzübersicht für Spartin (SPART) (AA 205-631) Antikörper (Biotin) (ABIN8041320)

Target: Spartin (SPART)

Reaktivität: Human, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Biotin

Applikation: ELISA, Western Blotting (WB), Immunohistochemistry (IHC)

Produktdetails

Bindungsspezifität: AA 205-631

Verwendungszweck: Anti-SPART Antibody Biotin Conjugated

Kreuzreaktivität (Details): No cross-reactivity with other proteins.

Aufreinigung: Immunogen affinity purified.

Immunogen: E.coli-derived human SPART recombinant protein (Position: H205-V631).

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Western blot, Optimal dilutions should be determined by end users. Immunohistochemistry (Paraffin-embedded Section), Optimal dilutions should be determined by end users. ELISA, Optimal dilutions should be determined by end users.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing.

Haltbarkeit: 12 months

Antigendetails

Target: Spartin (SPART)

Andere Bezeichnung: SPART

Hintergrund:

Background: Spartin is a protein that in humans is encoded by the SPG20 gene. This gene encodes a protein containing a MIT (Microtubule Interacting and Trafficking molecule) domain, and is implicated in regulating endosomal trafficking and mitochondria function. The protein localizes to mitochondria and partially co-localizes with microtubules. Stimulation with epidermal growth factor (EGF) results in protein translocation to the plasma membrane, and the protein functions in the degradation and intracellular trafficking of EGF receptor. Multiple alternatively spliced variants, encoding the same protein, have been identified. Mutations associated with this gene cause autosomal recessive spastic paraplegia 20 (Troyer syndrome).

Gene Full Name: spartin

Gen-ID: 23111

UniProt: Q8N0X7