Spartin (SPART) (Middle Region) Antikörper

Produktnummer ABIN2786078

Der Kaninchen Polyklonal anti-Spartin Antikörper (ABIN2786078) detektiert spezifisch Spartin in WB. Dieser Antikörper reagiert spezifisch mit Proben aus Human, Ratte, Maus, Zebrafisch (Danio rerio), Kaninchen, Pferd, Meerschweinchen, Hund und Rind (Kuh).

Kurzübersicht für Spartin (SPART) (Middle Region) Antikörper (ABIN2786078)

Target: Spartin (SPART)

Reaktivität: Human, Ratte, Maus, Zebrafisch (Danio rerio), Kaninchen, Pferd, Meerschweinchen, Hund, Rind (Kuh)

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails

Bindungsspezifität: Middle Region

Verwendungszweck: SPART Antibody - middle region

Sequenz: ASWVSWGLVK GAEITGKAIQ KGASKLRERI QPEEKPVEVS PAVTKGLYIA

Homologie: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 79%

Produktmerkmale: This is a rabbit polyclonal antibody against SPG20. It was validated on Western Blot using a cell lysate as a positive control.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human SPG20

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Kommentare:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP55162-100UG

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: prevent freeze-thaw cycles

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Antigendetails

Target: Spartin (SPART)

Andere Bezeichnung: SPART

Hintergrund:

Background Information: This gene encodes a protein containing a MIT (Microtubule Interacting and Trafficking molecule) domain, and is implicated in regulating endosomal trafficking and mitochondria function. The protein localizes to mitochondria and partially co-localizes with microtubules. Stimulation with epidermal growth factor (EGF) results in protein translocation to the plasma membrane, and the protein functions in the degradation and intracellular trafficking of EGF receptor. Multiple alternatively spliced variants, encoding the same protein, have been identified. Mutations associated with this gene cause autosomal recessive spastic paraplegia 20 (Troyer syndrome).

Gene Name: spartin

Alternative Symbols: SPG20, TAHCCP1

Protein Name: spartin

Molekulargewicht: 73kDa

Gen-ID: 23111

NCBI Accession: NP_055902

UniProt: Q8N0X7