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IFNAR1 Antikörper (AA 351-450)

This anti-IFNAR1 antibody (ABIN754063) is a Rabbit Polyclonal antibody detecting IFNAR1 in WB, ELISA, FACS, IF (cc), IF (p), IHC (p), IHC (fro). Suitable for Human, Mouse, Rat.
Produktnummer ABIN754063

Kurzübersicht für IFNAR1 Antikörper (AA 351-450) (ABIN754063)

Target

Alle IFNAR1 Antikörper anzeigen
IFNAR1 (Interferon alpha/beta Receptor 1 (IFNAR1))

Reaktivität

  • 100
  • 27
  • 24
  • 2
  • 2
  • 1
  • 1
Human, Maus, Ratte

Wirt

  • 91
  • 24
  • 1
  • 1
Kaninchen

Klonalität

  • 79
  • 35
  • 2
Polyklonal

Konjugat

  • 54
  • 11
  • 4
  • 4
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
Dieser IFNAR1 Antikörper ist unkonjugiert

Applikation

  • 48
  • 35
  • 31
  • 28
  • 24
  • 24
  • 9
  • 7
  • 5
  • 5
  • 4
  • 3
  • 2
  • 2
  • 1
  • 1
Western Blotting (WB), ELISA, Flow Cytometry (FACS), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))
  • Bindungsspezifität

    • 21
    • 16
    • 13
    • 9
    • 6
    • 4
    • 4
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 351-450

    Kreuzreaktivität

    Human, Maus, Ratte

    Homologie

    Cow,Sheep

    Aufreinigung

    Purified by Protein A.

    Immunogen

    KLH conjugated synthetic peptide derived from human IFNAR1

    Isotyp

    IgG
  • Applikationshinweise

    WB 1:300-5000
    ELISA 1:500-1000
    FCM 1:20-100
    IHC-P 1:200-400
    IHC-F 1:100-500
    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200

    Beschränkungen

    Nur für Forschungszwecke einsetzbar
  • Format

    Liquid

    Konzentration

    1 μg/μL

    Buffer

    0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

    Konservierungsmittel

    ProClin

    Vorsichtsmaßnahmen

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

    Lagerung

    4 °C,-20 °C

    Informationen zur Lagerung

    Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

    Haltbarkeit

    12 months
  • Target

    IFNAR1 (Interferon alpha/beta Receptor 1 (IFNAR1))

    Andere Bezeichnung

    IFNAR1

    Hintergrund

    Synonyms: AVP, IFRC, IFNAR, IFNBR, IFN-alpha-REC, Interferon alpha/beta receptor 1, IFN-R-1, IFN-alpha/beta receptor 1, Cytokine receptor class-II member 1, Cytokine receptor family 2 member 1, CRF2-1, Type I interferon receptor 1, IFNAR1

    Background: Component of the receptor for type I interferons, including interferons alpha, IFNB1 and IFNW1 (PubMed:2153461, PubMed:7665574, PubMed:10049744, PubMed:14532120, PubMed:15337770, PubMed:21854986). Functions in general as heterodimer with IFNAR2 (PubMed:7665574, PubMed:10049744, PubMed:21854986). Type I interferon binding activates the JAK-STAT signaling cascade, and triggers tyrosine phosphorylation of a number of proteins including JAKs, TYK2, STAT proteins and the IFNR alpha- and beta-subunits themselves (PubMed:7665574, PubMed:21854986). Can form an active IFNB1 receptor by itself and activate a signaling cascade that does not involve activation of the JAK-STAT pathway (By similarity).

    Gen-ID

    3454

    UniProt

    P17181

    Pathways

    JAK-STAT Signalweg, Hepatitis C
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