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IFNAR1 Antikörper (AA 351-450)

Dieses Kaninchen Polyklonal-Antikörper erkennt spezifisch IFNAR1 in WB, ELISA, FACS, IF (cc), IF (p), IHC (p) und IHC (fro). Er zeigt eine Reaktivität gegenüber Human, Maus und Ratte.
Produktnummer ABIN754063

Kurzübersicht für IFNAR1 Antikörper (AA 351-450) (ABIN754063)

Target

Alle IFNAR1 Antikörper anzeigen
IFNAR1 (Interferon alpha/beta Receptor 1 (IFNAR1))

Reaktivität

  • 100
  • 27
  • 24
  • 2
  • 2
  • 1
  • 1
Human, Maus, Ratte

Wirt

  • 91
  • 24
  • 1
  • 1
Kaninchen

Klonalität

  • 79
  • 35
  • 2
Polyklonal

Konjugat

  • 54
  • 11
  • 4
  • 4
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
Dieser IFNAR1 Antikörper ist unkonjugiert

Applikation

  • 48
  • 35
  • 31
  • 28
  • 24
  • 24
  • 9
  • 7
  • 5
  • 5
  • 4
  • 3
  • 2
  • 2
  • 1
  • 1
Western Blotting (WB), ELISA, Flow Cytometry (FACS), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))
  • Bindungsspezifität

    • 21
    • 16
    • 13
    • 9
    • 6
    • 4
    • 4
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 351-450

    Kreuzreaktivität

    Human, Maus, Ratte

    Homologie

    Cow,Sheep

    Aufreinigung

    Purified by Protein A.

    Immunogen

    KLH conjugated synthetic peptide derived from human IFNAR1

    Isotyp

    IgG
  • Applikationshinweise

    WB 1:300-5000
    ELISA 1:500-1000
    FCM 1:20-100
    IHC-P 1:200-400
    IHC-F 1:100-500
    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200

    Beschränkungen

    Nur für Forschungszwecke einsetzbar
  • Format

    Liquid

    Konzentration

    1 μg/μL

    Buffer

    0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

    Konservierungsmittel

    ProClin

    Vorsichtsmaßnahmen

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

    Lagerung

    4 °C,-20 °C

    Informationen zur Lagerung

    Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

    Haltbarkeit

    12 months
  • Target

    IFNAR1 (Interferon alpha/beta Receptor 1 (IFNAR1))

    Andere Bezeichnung

    IFNAR1

    Hintergrund

    Synonyms: AVP, IFRC, IFNAR, IFNBR, IFN-alpha-REC, Interferon alpha/beta receptor 1, IFN-R-1, IFN-alpha/beta receptor 1, Cytokine receptor class-II member 1, Cytokine receptor family 2 member 1, CRF2-1, Type I interferon receptor 1, IFNAR1

    Background: Component of the receptor for type I interferons, including interferons alpha, IFNB1 and IFNW1 (PubMed:2153461, PubMed:7665574, PubMed:10049744, PubMed:14532120, PubMed:15337770, PubMed:21854986). Functions in general as heterodimer with IFNAR2 (PubMed:7665574, PubMed:10049744, PubMed:21854986). Type I interferon binding activates the JAK-STAT signaling cascade, and triggers tyrosine phosphorylation of a number of proteins including JAKs, TYK2, STAT proteins and the IFNR alpha- and beta-subunits themselves (PubMed:7665574, PubMed:21854986). Can form an active IFNB1 receptor by itself and activate a signaling cascade that does not involve activation of the JAK-STAT pathway (By similarity).

    Gen-ID

    3454

    UniProt

    P17181

    Pathways

    JAK-STAT Signalweg, Hepatitis C
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