SIGMAR1 Antikörper (AA 1-154)

Produktnummer ABIN8037297

Der Kaninchen Polyklonal anti-SIGMAR1 Antikörper wird verwendet zum Nachweis von SIGMAR1 in Proben von Human, Maus, Ratte und Affe. Er wurde validiert für WB, ELISA und IHC.

Kurzübersicht für SIGMAR1 Antikörper (AA 1-154) (ABIN8037297)

Target: SIGMAR1 (sigma Non-Opioid Intracellular Receptor 1 (SIGMAR1))

Reaktivität: Human, Maus, Ratte, Affe

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser SIGMAR1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Güteklasse: Carrier-free

Produktdetails anti-SIGMAR1 Antikörper

Bindungsspezifität: AA 1-154

Verwendungszweck: Anti-Sigma1-receptor/SIGMAR1 Antibody

Kreuzreaktivität (Details): No cross-reactivity with other proteins

Produktmerkmale: Anti-Sigma1-receptor/SIGMAR1 Antibody. Tested in ELISA, IHC, WB applications. This antibody reacts with Human, Monkey, Mouse, Rat.

Aufreinigung: Immunogen affinity purified.

Immunogen: E.coli-derived human Sigma1-receptor/SIGMAR1 recombinant protein (Position: G1-H154).

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Western blot, 0.1-0.25 μg/mL, Human, Monkey, Mouse Immunohistochemistry(Paraffin-embedded Section), 2-5 μg/mL, Human, Mouse, Rat ELISA, 0.1-0.5 μg/mL, -

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Konzentration: 500 μg/mL

Buffer: Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.

Haltbarkeit: 12 months

Details zu SIGMAR1

Target: SIGMAR1 (sigma Non-Opioid Intracellular Receptor 1 (SIGMAR1))

Andere Bezeichnung: SIGMAR1

Hintergrund:

Background: The sigma-1 receptor (σ1R), one of two sigma receptor subtypes, is a chaperone protein at the endoplasmic reticulum (ER) that modulates calcium signaling through the IP3 receptor. In humans, the σ1 receptor is encoded by the SIGMAR1 gene. This gene encodes a receptor protein that interacts with a variety of psychotomimetic drugs, including cocaine and amphetamines. The receptor is believed to play an important role in the cellular functions of various tissues associated with the endocrine, immune, and nervous systems. As indicated by its previous name, opioid receptor sigma 1 (OPRS1), the product of this gene was erroneously thought to function as an opioid receptor, it is now thought to be a non-opioid receptor. Mutations in this gene has been associated with juvenile amyotrophic lateral sclerosis 16. Alternative splicing of this gene results in transcript variants encoding distinct isoforms.

Gene Full Name: sigma non-opioid intracellular receptor 1

Molekulargewicht: 25 kDa

Gen-ID: 10280

UniProt: Q99720

Pathways: SARS-CoV-2 Protein Interaktom