SETDB1 Antikörper (AA 20-871)

Produktnummer ABIN8036754

Der Kaninchen Polyklonal anti-SETDB1 Antikörper wird verwendet zum Nachweis von SETDB1 in Proben von Human. Er wurde validiert für WB, ELISA und FACS.

Kurzübersicht für SETDB1 Antikörper (AA 20-871) (ABIN8036754)

Target: SETDB1 (SET Domain, Bifurcated 1 (SETDB1))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser SETDB1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Flow Cytometry (FACS)

Güteklasse: Carrier-free

Produktdetails anti-SETDB1 Antikörper

Bindungsspezifität: AA 20-871

Verwendungszweck: Anti-SETDB1 Antibody

Kreuzreaktivität (Details): No cross-reactivity with other proteins

Homologie: Human SETDB1 shares 92.9% amino acid (aa) sequence identity with mouse SETDB1.

Produktmerkmale: Anti-SETDB1 Antibody. Tested in WB, Flow Cytometry, ELISA applications. This antibody reacts with Human.

Aufreinigung: Immunogen affinity purified.

Immunogen: E.coli-derived human SETDB1 recombinant protein (Position: E20-E871). Human SETDB1 shares 92.9% amino acid (aa) sequence identity with mouse SETDB1.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Western blot, 0.25-0.5 μg/mL, Human Flow Cytometry (Fixed), 1-3 μg/1x10⁶ cells, Human ELISA, 0.1-0.5 μg/mL

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Konzentration: 500 μg/mL

Buffer: Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.

Haltbarkeit: 12 months

Details zu SETDB1

Target: SETDB1 (SET Domain, Bifurcated 1 (SETDB1))

Andere Bezeichnung: SETDB1

Hintergrund:

Background: This gene encodes a histone methyltransferase which regulates histone methylation, gene silencing, and transcriptional repression. This gene has been identified as a target for treatment in Huntington Disease, given that gene silencing and transcription dysfunction likely play a role in the disease pathogenesis. Alternatively spliced transcript variants of this gene have been described.

Gene Full Name: SET domain bifurcated histone lysine methyltransferase 1

Molekulargewicht: 180 kDa

Gen-ID: 9869

UniProt: Q15047