SGK1 Antikörper (N-Term) (Biotin)

Produktnummer ABIN8036590

Der Biotin-konjugierte Kaninchen Polyklonal anti-SGK1 Antikörper (ABIN8036590) detektiert spezifisch SGK1 in WB, ELISA und IHC. Dieser Antikörper reagiert spezifisch mit Proben aus Human.

Kurzübersicht für SGK1 Antikörper (N-Term) (Biotin) (ABIN8036590)

Target: SGK1 (serum/glucocorticoid Regulated Kinase 1 (SGK1))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser SGK1 Antikörper ist konjugiert mit Biotin

Applikation: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Produktdetails anti-SGK1 Antikörper (Biotin)

Bindungsspezifität: N-Term

Verwendungszweck: Anti-SGK1 Antibody Biotin Conjugated

Spezifität: No cross reactivity with other proteins.

Kreuzreaktivität (Details): No cross-reactivity with other proteins

Homologie: different from the related mouse sequence by three amino acids,and from the related rat sequence by one amino acid.

Aufreinigung: Immunogen affinity purified.

Immunogen: A synthetic peptide corresponding to a sequence at the N-terminus of human SGK1, different from the related mouse sequence by three amino acids, and from the related rat sequence by one amino acid.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Western blot, Optimal dilutions should be determined by end users. Immunohistochemistry (Paraffin-embedded Section), Optimal dilutions should be determined by end users. ELISA, Optimal dilutions should be determined by end users.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing.

Haltbarkeit: 12 months

Details zu SGK1

Target: SGK1 (serum/glucocorticoid Regulated Kinase 1 (SGK1))

Andere Bezeichnung: SGK1

Hintergrund:

Background: Serine/threonine-protein kinase Sgk1, also called SGK1, encodes a serine/threonine protein kinase that plays an important role in cellular stress response. By fluorescence in situ hybridization, this gene is mapped to 6q23.2. This kinase activates certain potassium, sodium, and chloride channels, suggesting an involvement in the regulation of processes such as cell survival, neuronal excitability, and renal sodium excretion. High levels of expression of this gene may contribute to conditions such as hypertension and diabetic nephropathy. Several alternatively spliced transcript variants encoding different isoforms have been noted for this gene.

Gene Full Name: serum/glucocorticoid regulated kinase 1

Sequence Similarities: Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family.

Gen-ID: 6446

UniProt: O00141

Pathways: MAPK Signalweg, Notch Signalweg, Steroid Hormone Mediated Signaling Pathway