S100A8 Antikörper (AA 2-89) (HRP)

Produktnummer ABIN8034344

Dieser Kaninchen Polyklonal Antikörper detektiert spezifisch S100A8 in WB, IHC und ELISA. Es zeigt Reaktivität gegenüber Proben von Maus und Ratte.

Kurzübersicht für S100A8 Antikörper (AA 2-89) (HRP) (ABIN8034344)

Target: S100A8 (S100 Calcium Binding Protein A8 (S100A8))

Reaktivität: Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser S100A8 Antikörper ist konjugiert mit HRP

Applikation: Western Blotting (WB), Immunohistochemistry (IHC), ELISA

Produktdetails anti-S100A8 Antikörper (HRP)

Bindungsspezifität: AA 2-89

Verwendungszweck: Anti-MRP8/S100A8 Antibody HRP Conjugated

Spezifität: No cross reactivity with recombinant human S100A8 is observed.

Kreuzreaktivität (Details): No cross-reactivity with recombinant human S100A8 is observed.

Homologie: Mouse S100A8 shares 58.6%,80.5% amino acid (aa) sequence identity with human,rat S100A8,respectively.

Aufreinigung: Immunogen affinity purified.

Immunogen: E.coli-derived mouse S100A8 recombinant protein (Position: P2-E89). Mouse S100A8 shares 58.6% and 80.5% amino acid (aa) sequence identity with human and rat S100A8, respectively.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Western blot, Optimal dilutions should be determined by end users. Immunohistochemistry (Paraffin-embedded Section), Optimal dilutions should be determined by end users. ELISA, Optimal dilutions should be determined by end users.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4.

Lagerung: -20 °C

Informationen zur Lagerung: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing.

Haltbarkeit: 12 months

Details zu S100A8

Target: S100A8 (S100 Calcium Binding Protein A8 (S100A8))

Andere Bezeichnung: S100a8

Hintergrund:

Background: S100 calcium-binding protein A8 (S100A8) is a protein that in humans is encoded by the S100A8 gene. It is also known as calgranulin A. The protein encoded by this gene is a member of the S100 family of proteins containing 2 EF-hand calcium-binding motifs. S100 proteins are localized in the cytoplasm and/or nucleus of a wide range of cells, and involved in the regulation of a number of cellular processes such as cell cycle progression and differentiation. S100 genes include at least 13 members which are located as a cluster on chromosome 1q21. This protein may function in the inhibition of casein kinase and as a cytokine. Altered expression of this protein is associated with the disease cystic fibrosis.

Gene Full Name: S100 calcium binding protein A8 (calgranulin A)

Gen-ID: 20201

UniProt: P27005

Pathways: Transition Metal Ion Homeostasis, Positive Regulation of Endopeptidase Activity, S100 Proteine