Regulating Synaptic Membrane Exocytosis 1 (RIMS1) (AA 49-1456) Antikörper (Biotin)

Produktnummer ABIN8031057

Der Kaninchen Polyklonal anti-Regulating Synaptic Membrane Exocytosis 1 Antikörper wird verwendet zum Nachweis von Regulating Synaptic Membrane Exocytosis 1 in Proben von Ratte und Maus. Er wurde validiert für WB, ELISA und IHC.

Kurzübersicht für Regulating Synaptic Membrane Exocytosis 1 (RIMS1) (AA 49-1456) Antikörper (Biotin) (ABIN8031057)

Target: Regulating Synaptic Membrane Exocytosis 1 (RIMS1)

Reaktivität: Ratte, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Biotin

Applikation: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Produktdetails

Bindungsspezifität: AA 49-1456

Verwendungszweck: Anti-RIM1/RIMS1 Antibody Biotin Conjugated

Kreuzreaktivität (Details): No cross-reactivity with other proteins

Aufreinigung: Immunogen affinity purified.

Immunogen: E.coli-derived human RIM1/RIMS1 recombinant protein (Position: K49-E1456).

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Western blot, Optimal dilutions should be determined by end users. Immunohistochemistry (Paraffin-embedded Section), Optimal dilutions should be determined by end users. ELISA, Optimal dilutions should be determined by end users.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing.

Haltbarkeit: 12 months

Antigendetails

Target: Regulating Synaptic Membrane Exocytosis 1 (RIMS1)

Andere Bezeichnung: RIMS1

Hintergrund:

Background: The protein encoded by this gene is a RAS gene superfamily member that regulates synaptic vesicle exocytosis. This gene also plays a role in the regulation of voltage-gated calcium channels during neurotransmitter and insulin release. Mutations have suggested a role cognition and have been identified as the cause of cone-rod dystrophy type 7. Multiple transcript variants encoding different isoforms have been described for this gene.

Gene Full Name: regulating synaptic membrane exocytosis 1

Gen-ID: 22999116837

UniProt: Q86UR5, Q99NE5

Pathways: Synaptic Membrane, Synaptic Vesicle Exocytosis, Dicarboxylic Acid Transport, Regulation of long-term Neuronal Synaptic Plasticity