RAD51 Homolog B Antikörper (AA 22-384) (Cy3)

Produktnummer ABIN8030096

Dieser Kaninchen Polyklonal Antikörper detektiert spezifisch RAD51 Homolog B in FACS. Es zeigt Reaktivität gegenüber Proben von Human.

Kurzübersicht für RAD51 Homolog B Antikörper (AA 22-384) (Cy3) (ABIN8030096)

Target: RAD51 Homolog B (Rad51B)

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser RAD51 Homolog B Antikörper ist konjugiert mit Cy3

Applikation: Flow Cytometry (FACS)

Produktdetails anti-RAD51 Homolog B Antikörper (Cy3)

Bindungsspezifität: AA 22-384

Verwendungszweck: Anti-RAD51L1/RAD51B Antibody Cy3 Conjugated

Kreuzreaktivität (Details): No cross-reactivity with other proteins

Homologie: Human RAD51L1,RAD51B shares 85.8% amino acid (aa) sequence identity with mouse RAD51L1,RAD51B.

Aufreinigung: Immunogen affinity purified.

Immunogen: E.coli-derived human RAD51L1/RAD51B recombinant protein (Position: H22-F384). Human RAD51L1/RAD51B shares 85.8% amino acid (aa) sequence identity with mouse RAD51L1/RAD51B.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Flow Cytometry, 1-3 μg/1x10⁶ cells

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Haltbarkeit: 12 months

Details zu RAD51 Homolog B

Target: RAD51 Homolog B (Rad51B)

Andere Bezeichnung: RAD51B

Hintergrund:

Background: The protein encoded by this gene is a member of the RAD51 protein family. RAD51 family members are evolutionarily conserved proteins essential for DNA repair by homologous recombination. This protein has been shown to form a stable heterodimer with the family member RAD51C, which further interacts with the other family members, such as RAD51, XRCC2, and XRCC3. Overexpression of this gene was found to cause cell cycle G1 delay and cell apoptosis, which suggested a role of this protein in sensing DNA damage. Rearrangements between this locus and high mobility group AT-hook 2 (HMGA2, GeneID 8091) have been observed in uterine leiomyomata.

Gene Full Name: RAD51 paralog B

Gen-ID: 5890

UniProt: O15315

Pathways: DNA Reparatur