PCDHGA2 Antikörper (AA 132-444) (Fluoro594)

Produktnummer ABIN8028740

Dieser Kaninchen Polyklonal Antikörper detektiert spezifisch PCDHGA2 in FACS. Es zeigt Reaktivität gegenüber Proben von Human und Maus.

Kurzübersicht für PCDHGA2 Antikörper (AA 132-444) (Fluoro594) (ABIN8028740)

Target: PCDHGA2 (Protocadherin gamma Subfamily A, 2 (PCDHGA2))

Reaktivität: Human, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser PCDHGA2 Antikörper ist konjugiert mit Fluoro594

Applikation: Flow Cytometry (FACS)

Produktdetails anti-PCDHGA2 Antikörper (Fluoro594)

Bindungsspezifität: AA 132-444

Verwendungszweck: Anti-PCDHGA2 Antibody Fluoro594 Conjugated

Kreuzreaktivität (Details): No cross reactivity with other proteins.

Homologie: Human PCDHGA2 shares 60.3% amino acid (aa) sequence identity with mouse PCDHGA2.

Aufreinigung: Immunogen affinity purified.

Immunogen: E.coli-derived human PCDHGA2 recombinant protein (Position: R132-D444). Human PCDHGA2 shares 60.3% amino acid (aa) sequence identity with mouse PCDHGA2.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Flow Cytometry, Optimal dilutions should be determined by end users.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Haltbarkeit: 12 months

Details zu PCDHGA2

Target: PCDHGA2 (Protocadherin gamma Subfamily A, 2 (PCDHGA2))

Andere Bezeichnung: PCDHGA2

Hintergrund:

Background: This gene is a member of the protocadherin gamma gene cluster, one of three related clusters tandemly linked on chromosome five. These gene clusters have an immunoglobulin-like organization, suggesting that a novel mechanism may be involved in their regulation and expression. The gamma gene cluster includes 22 genes divided into 3 subfamilies. Subfamily A contains 12 genes, subfamily B contains 7 genes and 2 pseudogenes, and the more distantly related subfamily C contains 3 genes. The tandem array of 22 large, variable region exons are followed by a constant region, containing 3 exons shared by all genes in the cluster. Each variable region exon encodes the extracellular region, which includes 6 cadherin ectodomains and a transmembrane region. The constant region exons encode the common cytoplasmic region. These neural cadherin-like cell adhesion proteins most likely play a critical role in the establishment and function of specific cell-cell connections in the brain. Alternative splicing has been described for the gamma cluster genes.

Gene Full Name: protocadherin gamma subfamily A, 2

Gen-ID: 56113

UniProt: Q9Y5H1