PCDHGA2 Antikörper (AA 132-444)

Produktnummer ABIN7870515

Der Kaninchen Polyklonal anti-PCDHGA2 Antikörper wird verwendet zum Nachweis von PCDHGA2 in Proben von Human und Maus. Er wurde validiert für WB und ELISA.

Kurzübersicht für PCDHGA2 Antikörper (AA 132-444) (ABIN7870515)

Target: PCDHGA2 (Protocadherin gamma Subfamily A, 2 (PCDHGA2))

Reaktivität: Human, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser PCDHGA2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA

Produktdetails anti-PCDHGA2 Antikörper

Bindungsspezifität: AA 132-444

Verwendungszweck: PCDHGA2 Antibody / Protocadherin gamma A2

Aufreinigung: Antigen affinity chromatography

Immunogen: An E.coli-derived human recombinant protein (amino acids R132-D444) was used as the immunogen for the PCDHGA2 antibody.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal dilution of the PCDHGA2 antibody should be determined by the researcher.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: After reconstitution, the PCDHGA2 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

Details zu PCDHGA2

Target: PCDHGA2 (Protocadherin gamma Subfamily A, 2 (PCDHGA2))

Andere Bezeichnung: PCDHGA2

Hintergrund: This gene is a member of the protocadherin gamma gene cluster, one of three related clusters tandemly linked on chromosome five. These gene clusters have an immunoglobulin-like organization, suggesting that a novel mechanism may be involved in their regulation and expression. The gamma gene cluster includes 22 genes divided into 3 subfamilies. Subfamily A contains 12 genes, subfamily B contains 7 genes and 2 pseudogenes, and the more distantly related subfamily C contains 3 genes. The tandem array of 22 large, variable region exons are followed by a constant region, containing 3 exons shared by all genes in the cluster. Each variable region exon encodes the extracellular region, which includes 6 cadherin ectodomains and a transmembrane region. The constant region exons encode the common cytoplasmic region. These neural cadherin-like cell adhesion proteins most likely play a critical role in the establishment and function of specific cell-cell connections in the brain. Alternative splicing has been described for the gamma cluster genes.

UniProt: Q9Y5H1