PIAS3 Antikörper (N-Term) (PE)

Produktnummer ABIN8027319

Der Kaninchen Polyklonal anti-PIAS3 Antikörper wird verwendet zum Nachweis von PIAS3 in Proben von Human, Ratte und Maus. Er wurde validiert für FACS.

Kurzübersicht für PIAS3 Antikörper (N-Term) (PE) (ABIN8027319)

Target: PIAS3 (Protein Inhibitor of Activated STAT, 3 (PIAS3))

Reaktivität: Human, Ratte, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser PIAS3 Antikörper ist konjugiert mit PE

Applikation: Flow Cytometry (FACS)

Produktdetails anti-PIAS3 Antikörper (PE)

Bindungsspezifität: N-Term

Verwendungszweck: Anti-PIAS3 Antibody PE Conjugated

Spezifität: No cross reactivity with other proteins.

Kreuzreaktivität (Details): No cross-reactivity with other proteins.

Aufreinigung: Immunogen affinity purified.

Immunogen: A synthetic peptide corresponding to a sequence at the N-terminus of human PIAS3, which shares 97.6% amino acid (aa) sequence identity with both mouse and rat PIAS3.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Flow Cytometry, Optimal dilutions should be determined by end users.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Haltbarkeit: 12 months

Details zu PIAS3

Target: PIAS3 (Protein Inhibitor of Activated STAT, 3 (PIAS3))

Andere Bezeichnung: PIAS3

Hintergrund:

Background: E3 SUMO-protein ligase PIAS3 is an enzyme that in humans is encoded by the PIAS3 gene. This gene encodes a member of the PIAS [protein inhibitor of activated STAT (signal transducer and activator of transcription)] family of transcriptional modulators. The protein functions as a SUMO (small ubiquitin-like modifier)-E3 ligase which catalyzes the covalent attachment of a SUMO protein to specific target substrates. It ly binds to several transcription factors and either blocks or enhances their activity. Alternatively spliced transcript variants of this gene have been identified, but the full-length nature of some of these variants has not been determined.

Gene Full Name: protein inhibitor of activated STAT 3

Gen-ID: 10401

UniProt: Q9Y6X2

Pathways: JAK-STAT Signalweg