slc25a13 Antikörper (AA 351-450)

Produktnummer ABIN752908

Dieses Kaninchen Polyklonal-Antikörper erkennt spezifisch slc25a13 in WB, ELISA, IF (cc), IF (p), IHC (p) und IHC (fro). Er zeigt eine Reaktivität gegenüber Human.

Kurzübersicht für slc25a13 Antikörper (AA 351-450) (ABIN752908)

Target: slc25a13 (Solute Carrier Family 25, Member 13 (Citrin) (slc25a13))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser slc25a13 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Produktdetails anti-slc25a13 Antikörper

Bindungsspezifität: AA 351-450

Homologie: Human,Mouse,Rat,Dog,Cow,Pig,Horse,Chicken

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human SLC25A13

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:300-5000
ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Haltbarkeit: 12 months

Details zu slc25a13

Target: slc25a13 (Solute Carrier Family 25, Member 13 (Citrin) (slc25a13))

Andere Bezeichnung: SLC25A13

Hintergrund:

Synonyms: ARALAR2, Calcium binding mitochondrial carrier protein Aralar2, Citrin, CTLN2, Ctrn, Mitochondrial aspartate glutamate carrier 2, RGD1565889, Solute carrier family 25 citrin member 13, Solute carrier family 25 member 13 citrin, Solute carrier family 25 member 13, AI785475, CMC2_HUMAN.

Background: SLC25A13 is a member of the mitochondrial carrier family. It contains four EF-hand Ca(2+) binding motifs in the N-terminal domain, and localizes to mitochondria. It catalyzes the exchange of aspartate for glutamate and a proton across the inner mitochondrial membrane, and is stimulated by calcium on the external side of the inner mitochondrial membrane. Mutations in the SLC25A13 gene result in citrullinemia, type II. Multiple transcript variants encoding different isoforms have been found for this gene.

Gen-ID: 10165

Pathways: Ribonucleoside Biosynthetic Process, Dicarboxylic Acid Transport