Progesterone Receptor Antikörper (AA 595-933) (FITC)

Produktnummer ABIN8025467

Dieser Kaninchen Polyklonal Antikörper detektiert spezifisch Progesterone Receptor in FACS. Es zeigt Reaktivität gegenüber Proben von Human.

Kurzübersicht für Progesterone Receptor Antikörper (AA 595-933) (FITC) (ABIN8025467)

Target: Progesterone Receptor (PGR)

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Progesterone Receptor Antikörper ist konjugiert mit FITC

Applikation: Flow Cytometry (FACS)

Produktdetails anti-Progesterone Receptor Antikörper (FITC)

Bindungsspezifität: AA 595-933

Verwendungszweck: Anti-Progesterone Receptor/PGR Antibody FITC Conjugated

Spezifität: No cross reactivity with other proteins.

Kreuzreaktivität (Details): No cross-reactivity with other proteins

Homologie: Human Progesterone Receptor shares 95%,94% amino acid (aa) sequences identity with mouse,rat Progesterone Receptor,respectively.

Aufreinigung: Immunogen affinity purified.

Immunogen: E.coli-derived human Progesterone Receptor recombinant protein (Position: M595-K933). Human Progesterone Receptor shares 95% and 94% amino acid (aa) sequences identity with mouse and rat Progesterone Receptor, respectively.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Flow Cytometry, Optimal dilutions should be determined by end users.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Haltbarkeit: 12 months

Details zu Progesterone Receptor

Target: Progesterone Receptor (PGR)

Andere Bezeichnung: PGR

Hintergrund:

Background: The progesterone receptor (PR) is an intracellular steroid receptor that specially binds progesterone in humans. PR has been a member of the steroid receptor superfamily. It is encoded by a single PGR gene residing on chromosome 11q22. The PGR gene uses separate promoters and translational start sites to produce 2 isoforms, PRA and PRB, which are identical except for an additional 165 amino acids present only in the N terminus of PRB. It can be observed in human breast tissues. The proteins function as dimeric molecules in nuclei to regulate the transcription of target genes in a ligand-responsive manner.

Gene Full Name: progesterone receptor

Sequence Similarities: Belongs to the nuclear hormone receptor family. NR3 subfamily.

Gen-ID: 5241

UniProt: P06401

Pathways: Nuclear Receptor Transcription Pathway, Intracellular Steroid Hormone Receptor Signaling Pathway, Steroid Hormone Mediated Signaling Pathway, Smooth Muscle Cell Migration