PARL Antikörper (Middle Region) (Biotin)

Produktnummer ABIN8025207

Der Kaninchen Polyklonal anti-PARL Antikörper wird verwendet zum Nachweis von PARL in Proben von Human, Maus und Ratte. Er wurde validiert für ELISA, WB und IHC.

Kurzübersicht für PARL Antikörper (Middle Region) (Biotin) (ABIN8025207)

Target: PARL (Presenilin Associated, Rhomboid-Like (PARL))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser PARL Antikörper ist konjugiert mit Biotin

Applikation: ELISA, Western Blotting (WB), Immunohistochemistry (IHC)

Produktdetails anti-PARL Antikörper (Biotin)

Bindungsspezifität: Middle Region

Verwendungszweck: Anti-PARL Antibody Biotin Conjugated

Kreuzreaktivität (Details): No cross-reactivity with other proteins

Homologie: Human PARL shares 98.8% amino acid (aa) sequence identity with both mouse,rat PARL.

Aufreinigung: Immunogen affinity purified.

Immunogen: A synthetic peptide corresponding to a sequence in the middle region of human PARL. Human PARL shares 98.8% amino acid (aa) sequence identity with both mouse and rat PARL.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Western blot, Optimal dilutions should be determined by end users. Immunohistochemistry (Paraffin-embedded Section), Optimal dilutions should be determined by end users. ELISA, Optimal dilutions should be determined by end users.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing.

Haltbarkeit: 12 months

Details zu PARL

Target: PARL (Presenilin Associated, Rhomboid-Like (PARL))

Andere Bezeichnung: PARL

Hintergrund:

Background: This gene encodes a member of the rhomboid family of intramembrane serine proteases that is localized to the inner mitochondrial membrane. The encoded protein regulates mitochondrial remodeling and apoptosis through regulated substrate proteolysis. Proteolytic processing of the encoded protein results in the release of a small peptide, P-beta, which may transit to the nucleus. Mutations in this gene may be associated with Parkinson's disease.

Gene Full Name: presenilin associated rhomboid like

Gen-ID: 55486

UniProt: Q9H300

Pathways: Autophagie