PNKP Antikörper (AA 43-487)

Produktnummer ABIN8024396

Dieser Kaninchen Polyklonal Antikörper detektiert spezifisch PNKP in WB, ELISA, IF, ICC und FACS. Es zeigt Reaktivität gegenüber Proben von Human, Maus und Ratte.

Kurzübersicht für PNKP Antikörper (AA 43-487) (ABIN8024396)

Target: PNKP (Polynucleotide Kinase 3'-Phosphatase (PNKP))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser PNKP Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunocytochemistry (ICC), Flow Cytometry (FACS)

Güteklasse: Carrier-free

Produktdetails anti-PNKP Antikörper

Bindungsspezifität: AA 43-487

Verwendungszweck: Anti-PNKP Antibody

Kreuzreaktivität (Details): No cross-reactivity with other proteins

Homologie: Human PNKP shares 81.8% amino acid (aa) sequence identity with mouse PNKP.

Produktmerkmale: Anti-PNKP Antibody. Tested in WB, ICC/IF, Flow Cytometry, ELISA applications. This antibody reacts with Human, Mouse, Rat.

Aufreinigung: Immunogen affinity purified.

Immunogen: E.coli-derived human PNKP recombinant protein (Position: D43-E487). Human PNKP shares 81.8% amino acid (aa) sequence identity with mouse PNKP.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Western blot, 0.25-0.5 μg/mL, Human, Mouse, Rat Immunocytochemistry/Immunofluorescence, 5 μg/mL, Human Flow Cytometry (Fixed), 1-3 μg/1x10⁶ cells, Human ELISA, 0.1-0.5 μg/mL

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Konzentration: 500 μg/mL

Buffer: Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.

Haltbarkeit: 12 months

Details zu PNKP

Target: PNKP (Polynucleotide Kinase 3'-Phosphatase (PNKP))

Andere Bezeichnung: PNKP

Hintergrund:

Background: This locus represents a gene involved in DNA repair. In response to ionizing radiation or oxidative damage, the protein encoded by this locus catalyzes 5' phosphorylation and 3' dephosphorylation of nucleic acids. Mutations at this locus have been associated with microcephaly, seizures, and developmental delay.

Gene Full Name: polynucleotide kinase 3'-phosphatase

Molekulargewicht: 57 kDa

Gen-ID: 11284

UniProt: Q96T60

Pathways: DNA Reparatur, Nucleotide Phosphorylation