PNKP Antikörper (AA 43-487) (HRP)
Kurzübersicht für PNKP Antikörper (AA 43-487) (HRP) (ABIN8024392)
Target
Alle PNKP Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- AA 43-487
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Verwendungszweck
- Anti-PNKP Antibody HRP Conjugated
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Kreuzreaktivität (Details)
- No cross-reactivity with other proteins
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Homologie
- Human PNKP shares 81.8% amino acid (aa) sequence identity with mouse PNKP.
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Aufreinigung
- Immunogen affinity purified.
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Immunogen
- E.coli-derived human PNKP recombinant protein (Position: D43-E487). Human PNKP shares 81.8% amino acid (aa) sequence identity with mouse PNKP.
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Isotyp
- IgG
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Applikationshinweise
- Western blot, Optimal dilutions should be determined by end users. Immunohistochemistry (Paraffin-embedded Section), Optimal dilutions should be determined by end users. ELISA, Optimal dilutions should be determined by end users.
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Buffer
- Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- At -20°C for one year from date of receipt. Avoid repeated freezing and thawing.
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Haltbarkeit
- 12 months
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- PNKP (Polynucleotide Kinase 3'-Phosphatase (PNKP))
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Andere Bezeichnung
- PNKP
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Hintergrund
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Background: This locus represents a gene involved in DNA repair. In response to ionizing radiation or oxidative damage, the protein encoded by this locus catalyzes 5' phosphorylation and 3' dephosphorylation of nucleic acids. Mutations at this locus have been associated with microcephaly, seizures, and developmental delay.
Gene Full Name: polynucleotide kinase 3'-phosphatase
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Gen-ID
- 11284
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UniProt
- Q96T60
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Pathways
- DNA Reparatur, Nucleotide Phosphorylation
Target
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