PARN Antikörper (AA 1-301) (Fluoro647)

Produktnummer ABIN8023918

Der Fluoro647-konjugierte Maus Monoklonal anti-PARN Antikörper (Klon 11D8) (ABIN8023918) detektiert spezifisch PARN in FACS. Dieser Antikörper reagiert spezifisch mit Proben aus Human, Maus, Ratte und Affe.

Kurzübersicht für PARN Antikörper (AA 1-301) (Fluoro647) (ABIN8023918)

Target: PARN (Poly A Specific Ribonuclease (PARN))

Reaktivität: Human, Maus, Ratte, Affe

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser PARN Antikörper ist konjugiert mit Fluoro647

Applikation: Flow Cytometry (FACS)

Klon: 11D8

Produktdetails anti-PARN Antikörper (Fluoro647)

Bindungsspezifität: AA 1-301

Verwendungszweck: Anti-PARN Antibody (monoclonal, 11D8) Fluoro647 Conjugated

Spezifität: No cross reactivity with other proteins.

Kreuzreaktivität (Details): No cross-reactivity with other proteins.

Aufreinigung: Immunogen affinity purified.

Immunogen: E. coli-derived human PARN recombinant protein (Position: M1-Y301).

Isotyp: IgG2b

Anwendungsinformationen

Applikationshinweise: Flow Cytometry, Optimal dilutions should be determined by end users.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Haltbarkeit: 12 months

Details zu PARN

Target: PARN (Poly A Specific Ribonuclease (PARN))

Andere Bezeichnung: PARN

Hintergrund:

Background: Poly (A)-specific ribonuclease (PARN), also known as polyadenylate-specific ribonuclease or deadenylating nuclease (DAN), is an enzyme that in humans is encoded by the PARN gene. The protein encoded by this gene is a 3'-exoribonuclease, with similarity to the RNase D family of 3'-exonucleases. It prefers poly (A) as the substrate, hence, efficiently degrades poly (A) tails of mRNAs. Exonucleolytic degradation of the poly (A) tail is often the first step in the decay of eukaryotic mRNAs. This protein is also involved in silencing of certain maternal mRNAs during oocyte maturation and early embryonic development, as well as in nonsense-mediated decay (NMD) of mRNAs that contain premature stop codons.

Gene Full Name: poly(A)-specific ribonuclease

Gen-ID: 5073

UniProt: O95453