SERPINB2 Antikörper (AA 1-180) (Cy3)

Produktnummer ABIN8022869

Dieser Kaninchen Polyklonal Antikörper detektiert spezifisch SERPINB2 in FACS. Es zeigt Reaktivität gegenüber Proben von Human.

Kurzübersicht für SERPINB2 Antikörper (AA 1-180) (Cy3) (ABIN8022869)

Target: SERPINB2 (Plasminogen Activator Inhibitor 2 (SERPINB2))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser SERPINB2 Antikörper ist konjugiert mit Cy3

Applikation: Flow Cytometry (FACS)

Produktdetails anti-SERPINB2 Antikörper (Cy3)

Bindungsspezifität: AA 1-180

Verwendungszweck: Anti-SerpinB2 Antibody Cy3 Conjugated

Spezifität: No cross reactivity with other proteins.

Kreuzreaktivität (Details): No cross-reactivity with other proteins.

Homologie: Human SerpinB2 shares 70%,66% amino acid (aa) sequence identity with mouse,rat SerpinB2,respectively.

Aufreinigung: Immunogen affinity purified.

Immunogen: E.coli-derived human SerpinB2 recombinant protein (Position: M1-K180). Human SerpinB2 shares 70% and 66% amino acid (aa) sequence identity with mouse and rat SerpinB2, respectively.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Flow Cytometry, 1-3 μg/1x10⁶ cells

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Haltbarkeit: 12 months

Details zu SERPINB2

Target: SERPINB2 (Plasminogen Activator Inhibitor 2 (SERPINB2))

Andere Bezeichnung: SERPINB2

Substanzklasse: Amino Acid

Hintergrund:

Background: SERPINB2 is also known as PAI or PAI2. Plasminogen activator inhibitor-2 (placental PAI) is acoagulation factor that inactivates tPA and urokinase. It is present in most cells, especially monocytes/macrophages. PAI-2 exists in two forms, a 60- kDa extracellular glycosylated form and a 43- kDa intracellular form. It is present only at detectable quantities in blood during pregnancy, as it is produced by the placenta, and may explain partially the increased rate of thrombosisduring pregnancy. The majority of expressed PAI-2 remains unsecreted due to the presence of an inefficient internal signal peptide.

Gene Full Name: serpin family B member 2

Sequence Similarities: Belongs to the semaphorin family.

Gen-ID: 5055

UniProt: P05120

Pathways: Autophagie