PIK3C2A Antikörper (AA 22-1523) (APC)

Produktnummer ABIN8021897

Dieser Kaninchen Polyklonal Antikörper detektiert spezifisch PIK3C2A in FACS. Es zeigt Reaktivität gegenüber Proben von Human und Maus.

Kurzübersicht für PIK3C2A Antikörper (AA 22-1523) (APC) (ABIN8021897)

Target: PIK3C2A (Phosphoinositide-3-Kinase, Class 2, alpha Polypeptide (PIK3C2A))

Reaktivität: Human, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser PIK3C2A Antikörper ist konjugiert mit APC

Applikation: Flow Cytometry (FACS)

Produktdetails anti-PIK3C2A Antikörper (APC)

Bindungsspezifität: AA 22-1523

Verwendungszweck: Anti-PIK3C2A Antibody APC Conjugated

Kreuzreaktivität (Details): No cross-reactivity with other proteins

Homologie: Human PIK3C2A shares 89.7% amino acid (aa) sequence identity with mouse PIK3C2A.

Aufreinigung: Immunogen affinity purified.

Immunogen: E.coli-derived human PIK3C2A recombinant protein (Position: R22-E1523). Human PIK3C2A shares 89.7% amino acid (aa) sequence identity with mouse PIK3C2A.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Flow Cytometry, Optimal dilutions should be determined by end users.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Haltbarkeit: 12 months

Details zu PIK3C2A

Target: PIK3C2A (Phosphoinositide-3-Kinase, Class 2, alpha Polypeptide (PIK3C2A))

Andere Bezeichnung: PIK3C2A

Hintergrund:

Background: The protein encoded by this gene belongs to the phosphoinositide 3-kinase (PI3K) family. PI3-kinases play roles in signaling pathways involved in cell proliferation, oncogenic transformation, cell survival, cell migration, and intracellular protein trafficking. This protein contains a lipid kinase catalytic domain as well as a C-terminal C2 domain, a characteristic of class II PI3-kinases. C2 domains act as calcium-dependent phospholipid binding motifs that mediate translocation of proteins to membranes, and may also mediate protein-protein interactions. The PI3-kinase activity of this protein is not sensitive to nanomolar levels of the inhibitor wortmanin. This protein was shown to be able to be activated by insulin and may be involved in integrin-dependent signaling.

Gene Full Name: phosphatidylinositol-4-phosphate 3-kinase catalytic subunit type 2 alpha

Gen-ID: 5286

UniProt: O00443

Pathways: EGFR Signaling Pathway, Inositol Metabolic Process, Platelet-derived growth Factor Receptor Signaling