PDE8B Antikörper (C-Term)

Produktnummer ABIN8021568

Der Kaninchen Polyklonal anti-PDE8B Antikörper wird verwendet zum Nachweis von PDE8B in Proben von Human. Er wurde validiert für WB, IF und ICC.

Kurzübersicht für PDE8B Antikörper (C-Term) (ABIN8021568)

Target: PDE8B (phosphodiesterase 8B (PDE8B))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser PDE8B Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunofluorescence (IF), Immunocytochemistry (ICC)

Güteklasse: Carrier-free

Produktdetails anti-PDE8B Antikörper

Bindungsspezifität: C-Term

Verwendungszweck: Anti-PDE8B Antibody

Kreuzreaktivität (Details): No cross-reactivity with other proteins

Homologie: Human PDE8B shares 100% amino acid (aa) sequence identity with mouse PDE8B.

Produktmerkmale: Anti-PDE8B Antibody. Tested in WB, ICC, IF applications. This antibody reacts with Human.

Aufreinigung: Immunogen affinity purified.

Immunogen: A synthetic peptide corresponding to a sequence at the C-terminus of human PDE8B. Human PDE8B shares 100% amino acid (aa) sequence identity with mouse PDE8B.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Western blot, 0.25-0.5 μg/mL, Human Immunocytochemistry/Immunofluorescence, 5 μg/mL, Human Flow Cytometry (Fixed), 1-3 μg/1x10⁶ cells, Human

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Konzentration: 500 μg/mL

Buffer: Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.

Haltbarkeit: 12 months

Details zu PDE8B

Target: PDE8B (phosphodiesterase 8B (PDE8B))

Andere Bezeichnung: PDE8B

Hintergrund:

Background: The protein encoded by this gene is a cyclic nucleotide phosphodiesterase (PDE) that catalyzes the hydrolysis of the second messenger cAMP. The encoded protein, which does not hydrolyze cGMP, is resistant to several PDE inhibitors. Defects in this gene are a cause of autosomal dominant striatal degeneration (ADSD). Several transcript variants encoding different isoforms have been found for this gene.

Gene Full Name: phosphodiesterase 8B

Molekulargewicht: 99 kDa

Gen-ID: 8622

UniProt: O95263

Pathways: Negative Regulation of Hormone Secretion, cAMP Metabolic Process