CDK11 Antikörper (AA 21-120) (FITC)

Produktnummer ABIN752330

Der Kaninchen Polyklonal Anti-CDK11-Antikörper wurde für WB, IF (cc) und IF (p) validiert. Er ist geeignet, CDK11 in Proben von Human zu detektieren.

Kurzübersicht für CDK11 Antikörper (AA 21-120) (FITC) (ABIN752330)

Target: CDK11 (CDK11B) (Cyclin-Dependent Kinase 11B (CDK11B))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser CDK11 Antikörper ist konjugiert mit FITC

Applikation: Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Produktdetails anti-CDK11 Antikörper (FITC)

Bindungsspezifität: AA 21-120

Homologie: Human,Mouse,Rat,Dog,Cow,Sheep,Pig,Rabbit

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human CDK11

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Haltbarkeit: 12 months

Details zu CDK11

Target: CDK11 (CDK11B) (Cyclin-Dependent Kinase 11B (CDK11B))

Andere Bezeichnung: CDK11

Hintergrund:

Synonyms: Galactosyltransferase associated protein kinase p58/GTA, CD11B_HUMAN, CDK11B, CDC2L1, PITSLREA, PK58, CDK11-p110, CDK11-p46, CDK11-p58, CDK11, CDK11 p110, CDK11 p46, CDK11 p58, CLK-1, p58, p58CDC2L1, p58CLK-1, p58 CLK-1, PK58, Cyclin-dependent kinase 11B, Cell division cycle 2-like protein kinase 1, Cell division protein kinase 11B, Galactosyltransferase-associated protein kinase p58/GTA, PITSLRE serine/threonine-protein kinase CDC2L1.

Background: Summary: This gene encodes a member of the p34Cdc2 protein kinase family. p34Cdc2 kinase family members are known to be essential for eukaryotic cell cycle control. This gene is in close proximity to CDC2L2, a nearly identical gene in the same chromosomal region. The gene loci including this gene, CDC2L2, as well as metalloprotease MMP21/22, consist of two identical, tandemly linked genomic regions which are thought to be a part of the larger region that has been duplicated. This gene and CDC2L2 were shown to be deleted or altered frequently in neuroblastoma with amplified MYCN genes. The protein kinase encoded by this gene could be cleaved by caspases and was demonstrated to play roles in cell apoptosis. Several alternatively spliced variants of this gene have been reported. [provided by RefSeq, Jul 2008].

Gen-ID: 984

Pathways: Regulation of Lipid Metabolism by PPARalpha, M Phase