HRPT2 Antikörper (AA 119-520) (HRP)

Produktnummer ABIN8019456

Der Kaninchen Polyklonal anti-HRPT2 Antikörper wird verwendet zum Nachweis von HRPT2 in Proben von Human. Er wurde validiert für WB, ELISA und IHC.

Kurzübersicht für HRPT2 Antikörper (AA 119-520) (HRP) (ABIN8019456)

Target: HRPT2 (CDC73) (Parafibromin (CDC73))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser HRPT2 Antikörper ist konjugiert mit HRP

Applikation: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Produktdetails anti-HRPT2 Antikörper (HRP)

Bindungsspezifität: AA 119-520

Verwendungszweck: Anti-HRPT2/CDC73 Antibody HRP Conjugated

Spezifität: No cross reactivity with other proteins.

Kreuzreaktivität (Details): No cross-reactivity with other proteins

Homologie: Human HRPT2 shares 100%,99.8% amino acid (aa) sequence identity with mouse,rat HRPT2,respectively.

Aufreinigung: Immunogen affinity purified.

Immunogen: E.coli-derived human HRPT2 recombinant protein (Position: Q119-R520). Human HRPT2 shares 100% and 99.8% amino acid (aa) sequence identity with mouse and rat HRPT2, respectively.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Western blot, Optimal dilutions should be determined by end users. Immunohistochemistry (Paraffin-embedded Section), Optimal dilutions should be determined by end users. ELISA, Optimal dilutions should be determined by end users.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4.

Lagerung: -20 °C

Informationen zur Lagerung: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing.

Haltbarkeit: 12 months

Details zu HRPT2

Target: HRPT2 (CDC73) (Parafibromin (CDC73))

Andere Bezeichnung: CDC73

Hintergrund:

Background: Cell division cycle 73, also known as HRPT2, is a protein which in humans is encoded by the CDC73 gene. This gene encodes a tumor suppressor that is involved in transcriptional and post-transcriptional control pathways. The protein is a component of the the PAF protein complex, which associates with the RNA polymerase II subunit POLR2A and with a histone methyltransferase complex. And this protein appears to facilitate the association of 3' mRNA processing factors with actively-transcribed chromatin. Mutations in this gene have been linked to hyperparathyroidism-jaw tumor syndrome, familial isolated hyperparathyroidism, and parathyroid carcinoma.

Gene Full Name: cell division cycle 73

Sequence Similarities: Belongs to the CDC73 family.

Gen-ID: 79577

UniProt: Q6P1J9

Pathways: Cellular Response to Molecule of Bacterial Origin, Stem Cell Maintenance