HRPT2 Antikörper (AA 51-100)

Produktnummer ABIN7230498

Der Kaninchen Polyklonal anti-HRPT2 Antikörper wird verwendet zum Nachweis von HRPT2 in Proben von Human, Maus und Ratte. Er wurde validiert für WB und ELISA.

Kurzübersicht für HRPT2 Antikörper (AA 51-100) (ABIN7230498)

Target: HRPT2 (CDC73) (Parafibromin (CDC73))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser HRPT2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA

Produktdetails anti-HRPT2 Antikörper

Bindungsspezifität: AA 51-100

Verwendungszweck: Rabbit Anti-Parafibromin Polyclonal Antibody

Spezifität: This antibody detects endogenous levels of Parafibromin

Aufreinigung: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from part region of human Parafibromin protein at AA range: 51-100

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000,ELISA 1:10000-20000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Haltbarkeit: 12 months

Details zu HRPT2

Target: HRPT2 (CDC73) (Parafibromin (CDC73))

Andere Bezeichnung: Parafibromin

Hintergrund: Parafibromin, Cell division cycle protein 73 homolog, Hyperparathyroidism 2 proteinCDC73 encodes a tumor suppressor that is involved in transcriptional and post-transcriptional control pathways. The protein is a component of the the PAF protein complex, which associates with the RNA polymerase II subunit POLR2A and with a histone methyltransferase complex. This protein appears to facilitate the association of 3' mRNA processing factors with actively-transcribed chromatin. Mutations in CDC73 have been linked to hyperparathyroidism-jaw tumor syndrome, familial isolated hyperparathyroidism, and parathyroid carcinoma.

Molekulargewicht: 60kD

Gen-ID: 79577

UniProt: Q6P1J9

Pathways: Cellular Response to Molecule of Bacterial Origin, Stem Cell Maintenance