OPA1 Antikörper (AA 296-562) (Fluoro550)

Produktnummer ABIN8018227

Der Fluoro550-konjugierte Kaninchen Polyklonal anti-OPA1 Antikörper (ABIN8018227) detektiert spezifisch OPA1 in FACS. Dieser Antikörper reagiert spezifisch mit Proben aus Human, Ratte und Maus.

Kurzübersicht für OPA1 Antikörper (AA 296-562) (Fluoro550) (ABIN8018227)

Target: OPA1 (Optic Atrophy 1 (Autosomal Dominant) (OPA1))

Reaktivität: Human, Ratte, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser OPA1 Antikörper ist konjugiert mit Fluoro550

Applikation: Flow Cytometry (FACS)

Produktdetails anti-OPA1 Antikörper (Fluoro550)

Bindungsspezifität: AA 296-562

Verwendungszweck: Anti-OPA1 Antibody Fluoro550 Conjugated

Kreuzreaktivität (Details): No cross-reactivity with other proteins.

Aufreinigung: Immunogen affinity purified.

Immunogen: E.coli-derived human OPA1 recombinant protein (Position: D296-Q562).

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Flow Cytometry, Optimal dilutions should be determined by end users.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Haltbarkeit: 12 months

Details zu OPA1

Target: OPA1 (Optic Atrophy 1 (Autosomal Dominant) (OPA1))

Andere Bezeichnung: OPA1

Hintergrund:

Background: Dynamin-like 120 kDa protein, mitochondrial is a protein that in humans is encoded by the OPA1 gene. It is mapped to 3q29. This protein regulates mitochondrial fusion and cristae structure in the inner mitochondrial membrane (IMM) and contributes to ATP synthesis and apoptosis. This gene product is a nuclear-encoded mitochondrial protein with similarity to dynamin-related GTPases. It is a component of the mitochondrial network. Mutations in this gene have been associated with optic atrophy type 1, which is a dominantly inherited optic neuropathy resulting in progressive loss of visual acuity, leading in many cases to legal blindness. Multiple transcript variants encoding different isoforms have been found for this gene.

Gene Full Name: OPA1 mitochondrial dynamin like GTPase

Gen-ID: 4976

UniProt: O60313

Pathways: Tube Formation