OPA1 Antikörper (AA 183-418)

Produktnummer ABIN7150845

Produktdetails anti-OPA1 Antikörper

Target: OPA1 (Optic Atrophy 1 (Autosomal Dominant) (OPA1))

Bindungsspezifität: AA 183-418

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser OPA1 Antikörper ist unkonjugiert

Applikation: ELISA, Immunohistochemistry (IHC)

Kreuzreaktivität: Human

Aufreinigung: >95%, Protein G purified

Immunogen: Recombinant Human Dynamin-like 120 kDa protein, mitochondrial protein (183-418AA)

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Recommended dilution: IHC:1:200-1:500,

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C,-80 °C

Informationen zur Lagerung: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Details zu OPA1

Target: OPA1 (Optic Atrophy 1 (Autosomal Dominant) (OPA1))

Andere Bezeichnung: OPA1 (OPA1 Produkte)

Synonyme: 1200011N24Rik antikoerper, AI225888 antikoerper, AI847218 antikoerper, lilr3 antikoerper, mKIAA0567 antikoerper, MGM1 antikoerper, NPG antikoerper, NTG antikoerper, largeG antikoerper, fk62d06 antikoerper, wu:fb77a10 antikoerper, wu:fk62d06 antikoerper, zgc:92092 antikoerper, OPA1, mitochondrial dynamin like GTPase antikoerper, optic atrophy 1 (autosomal dominant) antikoerper, Opa1 antikoerper, OPA1 antikoerper, opa1 antikoerper

Hintergrund:

Background: Dynamin-related GTPase required for mitochondrial fusion and regulation of apoptosis. May form a diffusion barrier for proteins stored in mitochondrial cristae. Proteolytic processing in response to intrinsic apoptotic signals may lead to disassembly of OPA1 oligomers and release of the caspase activator cytochrome C (CYCS) into the mitochondrial intermembrane space. May also play a role in mitochondrial genome maintenance.

Aliases: Dynamin like 120 kDa protein antibody, Dynamin like 120 kDa protein, mitochondrial antibody, Dynamin-like 120 kDa protein, form S1 antibody, FLJ12460 antibody, Juvenile kjer type optic atrophy antibody, KIAA0567 antibody, KJER type antibody, Large GTP binding protein antibody, largeG antibody, MGM1 antibody, Mitochondrial dynamin like 120 kDa protein antibody, Mitochondrial dynamin like GTPase antibody, NPG antibody, NTG antibody, OAK antibody, OPA 1 antibody, opa1 antibody, OPA1 gene antibody, OPA1_HUMAN antibody, Optic atrophy 1 (autosomal dominant) antibody, OPTIC ATROPHY 1 antibody, Optic atrophy 1 gene protein antibody, Optic atrophy 1 homolog (human) antibody, Optic atrophy protein 1 antibody, Optic atrophy protein 1 homolog antibody

UniProt: O60313

Pathways: Tube Formation