OCRL Antikörper (AA 1-901) (Fluoro550)

Produktnummer ABIN8017919

Dieser Kaninchen Polyklonal Antikörper detektiert spezifisch OCRL in FACS. Es zeigt Reaktivität gegenüber Proben von Human.

Kurzübersicht für OCRL Antikörper (AA 1-901) (Fluoro550) (ABIN8017919)

Target: OCRL (Oculocerebrorenal Syndrome of Lowe (OCRL))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser OCRL Antikörper ist konjugiert mit Fluoro550

Applikation: Flow Cytometry (FACS)

Produktdetails anti-OCRL Antikörper (Fluoro550)

Bindungsspezifität: AA 1-901

Verwendungszweck: Anti-OCRL Antibody Fluoro550 Conjugated

Kreuzreaktivität (Details): No cross-reactivity with other proteins.

Aufreinigung: Immunogen affinity purified.

Immunogen: E.coli-derived human OCRL recombinant protein (Position: M1-D901).

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Flow Cytometry, Optimal dilutions should be determined by end users.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Haltbarkeit: 12 months

Details zu OCRL

Target: OCRL (Oculocerebrorenal Syndrome of Lowe (OCRL))

Andere Bezeichnung: OCRL

Hintergrund:

Background: Inositol polyphosphate 5-phosphatase OCRL-1, also known as Lowe oculocerebrorenal syndrome protein, is an enzyme encoded by the OCRL gene located on the X chromosome in humans. This gene encodes an inositol polyphosphate 5-phosphatase. This protein is involved in regulating membrane trafficking and is located in numerous subcellular locations including the trans-Golgi network, clathrin-coated vesicles and, endosomes and the plasma membrane. This protein may also play a role in primary cilium formation. Mutations in this gene cause oculocerebrorenal syndrome of Lowe and also Dent disease. Alternate splicing results in multiple transcript variants.

Gene Full Name: OCRL inositol polyphosphate-5-phosphatase

Gen-ID: 4952

UniProt: Q01968

Pathways: Inositol Metabolic Process