NHEJ1 Antikörper (AA 1-273) (Fluoro594)

Produktnummer ABIN8016093

Der Kaninchen Polyklonal anti-NHEJ1 Antikörper wird verwendet zum Nachweis von NHEJ1 in Proben von Human und Maus. Er wurde validiert für FACS.

Kurzübersicht für NHEJ1 Antikörper (AA 1-273) (Fluoro594) (ABIN8016093)

Target: NHEJ1 (Nonhomologous End-Joining Factor 1 (NHEJ1))

Reaktivität: Human, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser NHEJ1 Antikörper ist konjugiert mit Fluoro594

Applikation: Flow Cytometry (FACS)

Produktdetails anti-NHEJ1 Antikörper (Fluoro594)

Bindungsspezifität: AA 1-273

Verwendungszweck: Anti-XLF/NHEJ1 Antibody Fluoro594 Conjugated

Spezifität: No cross reactivity with other proteins.

Kreuzreaktivität (Details): No cross-reactivity with other proteins.

Aufreinigung: Immunogen affinity purified.

Immunogen: E.coli-derived human XLF/NHEJ1 recombinant protein (Position: M1-E273).

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Flow Cytometry, Optimal dilutions should be determined by end users.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Haltbarkeit: 12 months

Details zu NHEJ1

Target: NHEJ1 (Nonhomologous End-Joining Factor 1 (NHEJ1))

Andere Bezeichnung: NHEJ1

Hintergrund:

Background: Non-homologous end-joining factor 1 (NHEJ1), also known as Cernunnos or XRCC4-like factor (XLF), is a protein that in humans is encoded by the NHEJ1 gene. It is mapped to 2q35. Double-strand breaks in DNA result from genotoxic stresses and are among the most damaging of DNA lesions. This gene encodes a DNA repair factor essential for the nonhomologous end-joining pathway, which preferentially mediates repair of double-stranded breaks. Mutations in this gene cause different kinds of severe combined immunodeficiency disorders.

Gene Full Name: non-homologous end joining factor 1

Gen-ID: 79840

UniProt: Q9H9Q4

Pathways: DNA Reparatur