NK2 Homeobox 5 Antikörper (AA 15-132) (Fluoro594)

Produktnummer ABIN8015784

Der Kaninchen Polyklonal anti-NK2 Homeobox 5 Antikörper wird verwendet zum Nachweis von NK2 Homeobox 5 in Proben von Human. Er wurde validiert für FACS.

Kurzübersicht für NK2 Homeobox 5 Antikörper (AA 15-132) (Fluoro594) (ABIN8015784)

Target: NK2 Homeobox 5 (NKX2-5)

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser NK2 Homeobox 5 Antikörper ist konjugiert mit Fluoro594

Applikation: Flow Cytometry (FACS)

Produktdetails anti-NK2 Homeobox 5 Antikörper (Fluoro594)

Bindungsspezifität: AA 15-132

Verwendungszweck: Anti-Nkx2.5/NKX2-5 Antibody Fluoro594 Conjugated

Kreuzreaktivität (Details): No cross-reactivity with other proteins.

Aufreinigung: Immunogen affinity purified.

Immunogen: E.coli-derived human Nkx2.5/NKX2-5 recombinant protein (Position: K15-R132).

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Flow Cytometry, Optimal dilutions should be determined by end users.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Haltbarkeit: 12 months

Details zu NK2 Homeobox 5

Target: NK2 Homeobox 5 (NKX2-5)

Andere Bezeichnung: NKX2-5

Hintergrund:

Background: Homeobox protein Nkx-2.5, also known as NKX2E or CSX is a protein that in humans is encoded by the NKX2-5 gene. It is mapped to 5q35.1. Homeobox-containing genes play critical roles in regulating tissue-specific gene expression essential for tissue differentiation, as well as determining the temporal and spatial patterns of development. Nkx2.5 and Tbx5 ly bound to the promoter of the gene encoding cardiac-specific natriuretic peptide precursor type A (NPPA) in tandem, and both transcription factors showed synergistic activation. The cardiac homeobox protein Nkx2.5 is essential in cardiac development, and mutations in CSX (which encodes Nkx2.5) cause various congenital heart malformations.

Gene Full Name: NK2 homeobox 5

Gen-ID: 1482

UniProt: P52952

Pathways: Regulation of Muscle Cell Differentiation, Skeletal Muscle Fiber Development