NDFIP2 Antikörper (AA 16-336) (Fluoro550)

Produktnummer ABIN8014144

Der Fluoro550-konjugierte Kaninchen Polyklonal anti-NDFIP2 Antikörper (ABIN8014144) detektiert spezifisch NDFIP2 in FACS. Dieser Antikörper reagiert spezifisch mit Proben aus Human.

Kurzübersicht für NDFIP2 Antikörper (AA 16-336) (Fluoro550) (ABIN8014144)

Target: NDFIP2 (Nedd4 Family Interacting Protein 2 (NDFIP2))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser NDFIP2 Antikörper ist konjugiert mit Fluoro550

Applikation: Flow Cytometry (FACS)

Produktdetails anti-NDFIP2 Antikörper (Fluoro550)

Bindungsspezifität: AA 16-336

Verwendungszweck: Anti-NDFIP2 Antibody Fluoro550 Conjugated

Kreuzreaktivität (Details): No cross-reactivity with other proteins.

Aufreinigung: Immunogen affinity purified.

Immunogen: E.coli-derived human NDFIP2 recombinant protein (Position: M16-L336).

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Flow Cytometry, Optimal dilutions should be determined by end users.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Haltbarkeit: 12 months

Details zu NDFIP2

Target: NDFIP2 (Nedd4 Family Interacting Protein 2 (NDFIP2))

Andere Bezeichnung: NDFIP2

Hintergrund:

Background: NEDD4 family-interacting protein 2 is a protein that in humans is encoded by the NDFIP2 gene. The NEDD4 family-interacting protein 1 (NDFIP1) belongs to a small group of evolutionarily conserved proteins with three transmembrane domains and is an integral Golgi membrane protein. It is a potential target for ubiquitination by the Nedd4 family of proteins. NDFIP1 is strongly expressed in surviving neurons following acute cortical brain injury, and overexpression in cultured cortical neurons increased survival following growth factor starvation, suggesting that NDFIP1 may play a role in neuronal survival. NDFIP1 and the related protein NDFIP2 are thought to interact with and regulate multiple components of the EGF and PTEN/Akt signaling pathways. Recent studies suggest that NDFIP1 may also play a role in Th17 differentiation by limiting the production of proinflammatory cytokines.

Gene Full Name: Nedd4 family interacting protein 2

Gen-ID: 54602

UniProt: Q9NV92

Pathways: Negative Regulation of Transporter Activity, SARS-CoV-2 Protein Interaktom