NDFIP2 Antikörper (Middle Region)

Produktnummer ABIN2783749

Produktdetails anti-NDFIP2 Antikörper

Target: NDFIP2 (Nedd4 Family Interacting Protein 2 (NDFIP2))

Bindungsspezifität: Middle Region

Reaktivität: Human, Maus, Pferd, Ratte, Rind (Kuh), Hund, Zebrafisch (Danio rerio), Meerschweinchen, Schwein, Kaninchen

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser NDFIP2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Sequenz: SFCITNTIAG RYGAICGFGL SLIKWILIVR FSDYFTGYFN GQYWLWWIFL

Homologie: Cow: 100%, Dog: 100%, Guinea Pig: 79%, Horse: 100%, Human: 100%, Mouse: 100%, Pig: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 100%

Produktmerkmale: This is a rabbit polyclonal antibody against NDFIP2. It was validated on Western Blot.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human NDFIP2

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 336 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu NDFIP2

Target: NDFIP2 (Nedd4 Family Interacting Protein 2 (NDFIP2))

Andere Bezeichnung: NDFIP2 (NDFIP2 Produkte)

Synonyme: MGC68708 antikoerper, DKFZp459H0627 antikoerper, N4WBP5A antikoerper, 0710001O20Rik antikoerper, 2810436B12Rik antikoerper, 9130207N19Rik antikoerper, N4wbp5a antikoerper, mKIAA1165 antikoerper, Nedd4 family interacting protein 2 S homeolog antikoerper, Nedd4 family interacting protein 2 antikoerper, ndfip2.S antikoerper, NDFIP2 antikoerper, ndfip2 antikoerper, Ndfip2 antikoerper

Hintergrund: NDFIP2 activates HECT domain-containing E3 ubiquitin-protein ligases, including ITCH, NEDD4, NEDD4L, SMURF2, WWP1 and WWP2, and consequently modulates the stability of their targets. As a result, NDFIP2 may control many cellular processes. NDFIP2 recruits ITCH, NEDD4 and SMURF2 to endosomal membranes. NDFIP2 may modulate EGFR signaling.
Alias Symbols: FLJ25842, KIAA1165, N4wbp5a, N4WBP5A
Protein Interaction Partner: UBC, NEDD4L, NEDD4, ELAVL1, ITCH, WWP2, SRC, PTEN, LYN, FYN, EGFR, SMURF1, SLC11A2,
Protein Size: 336

Molekulargewicht: 36 kDa

Gen-ID: 54602

NCBI Accession: NM_019080, NP_061953

UniProt: Q9NV92

Pathways: Negative Regulation of Transporter Activity, SARS-CoV-2 Protein Interaktom